2'-Azido-2'-deoxyuridine
Based on 1 Customer Validation
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 26929-65-7
- Formula: C9H11N5O5
- Molecular Weight:269.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
2'-Azido-2'-deoxyuridine (N3dUrd) has IC50s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 26929-65-7
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Appearance Solid
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Molecular Weight 269.21
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Formula C9H11N5O5
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Color White to off-white
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SMILES
O=C(C=C1)NC(N1[C@@H]([C@H](N=[N+]=[N-])[C@@H]2O)O[C@@H]2CO)=O
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Synonyms
N3dUrd
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (371.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7146 mL | 18.5729 mL | 37.1457 mL | 92.8643 mL |
| 5 mM | 0.7429 mL | 3.7146 mL | 7.4291 mL | 18.5729 mL | |
| 10 mM | 0.3715 mL | 1.8573 mL | 3.7146 mL | 9.2864 mL | |
| 15 mM | 0.2476 mL | 1.2382 mL | 2.4764 mL | 6.1910 mL | |
| 20 mM | 0.1857 mL | 0.9286 mL | 1.8573 mL | 4.6432 mL | |
| 25 mM | 0.1486 mL | 0.7429 mL | 1.4858 mL | 3.7146 mL | |
| 30 mM | 0.1238 mL | 0.6191 mL | 1.2382 mL | 3.0955 mL | |
| 40 mM | 0.0929 mL | 0.4643 mL | 0.9286 mL | 2.3216 mL | |
| 50 mM | 0.0743 mL | 0.3715 mL | 0.7429 mL | 1.8573 mL | |
| 60 mM | 0.0619 mL | 0.3095 mL | 0.6191 mL | 1.5477 mL | |
| 80 mM | 0.0464 mL | 0.2322 mL | 0.4643 mL | 1.1608 mL | |
| 100 mM | 0.0371 mL | 0.1857 mL | 0.3715 mL | 0.9286 mL |
2'-Azido-2'-deoxyuridine Related Classifications
HY-135957 Related Classifications
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