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Cat. No.: HY-181935

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Antibiotic adjuvant 4

Antibiotic adjuvant 4 (Compound 13) is an Antibiotic adjuvant and efflux pump inhibitor. Antibiotic adjuvant 4 exhibits potent efflux pump inhibitory activity. Antibiotic adjuvant 4 significantly downregulates virulence-related genes of Staphylococcus aureus when used alone or in combination with antibiotics. Antibiotic adjuvant 4 enhances the efficacy of Ciprofloxacin (HY-B0356) against multiagent-resistant Staphylococcus aureus strains.

For research use only. We do not sell to patients.

CAS No.: 2493985-50-3
Formula: C₂₁H₃₆O₂
Molecular Weight:320.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antibiotic adjuvant 4 Chemical Structure

CAS No.: 2493985-50-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Antibiotic adjuvant 4 (1.56-50 μM; 20 h) sensitizes multiagent-resistant Staphylococcus aureus SA4 to ciprofloxacin, reducing the MIC of Ciprofloxacin from 94.84 μM when used alone to 17.12 μM when used in combination with ciprofloxacin^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2493985-50-3
Molecular Weight 320.51
Formula C₂₁H₃₆O₂
SMILES

C[C@@]12[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CCC4)([H])C[C@H](OCCO)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Brdová D, et al. Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation. Eur J Med Chem. 2026;308:118716. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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