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Referencia número: HY-181935

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Antibiotic adjuvant 4

Antibiotic adjuvant 4 (Compound 13) is an Antibiotic adjuvant and efflux pump inhibitor. Antibiotic adjuvant 4 exhibits potent efflux pump inhibitory activity. Antibiotic adjuvant 4 significantly downregulates virulence-related genes of Staphylococcus aureus when used alone or in combination with antibiotics. Antibiotic adjuvant 4 enhances the efficacy of Ciprofloxacin (HY-B0356) against multiagent-resistant Staphylococcus aureus strains.

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No. CAS: 2493985-50-3
Fòrmula: C₂₁H₃₆O₂
Peso molecular:320.51

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antibiotic adjuvant 4 Chemical Structure

No. CAS: 2493985-50-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
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Actividad biológica

Descripciòn

In Vitro

Antibiotic adjuvant 4 (1.56-50 μM; 20 h) sensitizes multiagent-resistant Staphylococcus aureus SA4 to ciprofloxacin, reducing the MIC of Ciprofloxacin from 94.84 μM when used alone to 17.12 μM when used in combination with ciprofloxacin^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2493985-50-3
Peso molecular 320.51
Fòrmula C₂₁H₃₆O₂
SMILES

C[C@@]12[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CCC4)([H])C[C@H](OCCO)CC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Brdová D, et al. Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation. Eur J Med Chem. 2026;308:118716. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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