Flavipucine
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 38473-18-6
- Formula: C12H15NO4
- Molecular Weight:237.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
1.6 μM
Compound: (-)-1
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Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
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[PMID: 30935798] |
Chemical Information
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CAS No. 38473-18-6
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Molecular Weight 237.25
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Formula C12H15NO4
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SMILES
CC(C)CC([C@H]1[C@]2(C(C=C(NC2=O)C)=O)O1)=O
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Synonyms
Flavipucin
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kusakabe Y, et al. Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1390-1394. [Content Brief]
[2]. Boya P CA, et al. Antiprotozoal Natural Products from Endophytic Fungi Associated with Cacao and Coffee. Metabolites. 2024 Oct 25;14(11):575. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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