1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. DBCO-NHS ester 3

DBCO-NHS ester 3 

Cat. No.: HY-115545
Handling Instructions

DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC).

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DBCO-NHS ester 3 Chemical Structure

DBCO-NHS ester 3 Chemical Structure

CAS No. : 1393350-27-0

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Description

DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

IC50 & Target[1]

Cleavable

 

Molecular Weight

416.43

Formula

C₂₄H₂₀N₂O₅

CAS No.

1393350-27-0

SMILES

O=C(CC1)N(OC(CCCC(N2C3=CC=CC=C3C#CC(C=CC=C4)=C4C2)=O)=O)C1=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DBCO-NHS ester 3ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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DBCO-NHS ester 3
Cat. No.:
HY-115545
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