HIV-1 protease-IN-1
HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].
For research use only. We do not sell to patients.
- CAS No.: 2765293-30-7
- Formula: C25H35N3O6S
- Molecular Weight:505.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | CC50 |
>200 μM
Compound: 1e
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Cytotoxicity against human HEK-293T cells after 24 hrs by CCK-8 assay
Cytotoxicity against human HEK-293T cells after 24 hrs by CCK-8 assay
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[PMID: 35278855] |
Chemical Information
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CAS No. 2765293-30-7
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Molecular Weight 505.63
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Formula C25H35N3O6S
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SMILES
O=C(N[C@H]([C@@H](CN(S(C1=CC=C(C=C1)O)(=O)=O)CC(C)C)O)CC2=CC=CC=C2)[C@@H]3COCCN3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 protease-IN-1 Related Classifications
HY-144688 Related Classifications
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