2765293-30-7
Chemical Structure
HIV-1 protease-IN-1
- CAS No.: 2765293-30-7
- Formula:C25H35N3O6S
- Molecular Weight:505.63
IUPAC Name: (S)-N-((2S,3R)-3-hydroxy-4-((4-hydroxy-N-isobutylphenyl)sulfonamido)-1-phenylbutan-2-yl)morpholine-3-carboxamide
InChIKey: QSIGJISDQQMQLD-KMDXXIMOSA-N
SMILES: O=C(N[C@H]([C@@H](CN(S(C1=CC=C(C=C1)O)(=O)=O)CC(C)C)O)CC2=CC=CC=C2)[C@@H]3COCCN3
Biological Activity: HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie[1].
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HIV-1 protease-IN-1 | HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC50 of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC50 value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC50 value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC50 value of 8.23 nM against C-HIV strain Indie. | |||||||||||||||||||||
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Keywords
