Antitrypanosomal agent 17
Antitrypanosomal agent 17 (Compd 7a) possesses antiamastigote activity, with an IC50 of 0.03 μM against T. congolense strain IL3000.
For research use only. We do not sell to patients.
- Formula: C19H15N3O4
- Molecular Weight:349.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
>100 μM
Compound: 7a
|
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
Cytotoxicity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin staining based analysis
|
[PMID: 37859713] |
| Vero | IC50 |
>100 μM
Compound: 7a
|
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
Cytotoxicity against African green monkey Vero cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based analysis
|
[PMID: 37859713] |
Chemical Information
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Molecular Weight 349.34
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Formula C19H15N3O4
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SMILES
O=[N+]([O-])C(O1)=CC=C1/C=N/N=C/C2=CC=C(OCC3=CC=CC=C3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)