HIV-1 inhibitor-48

Cat. No.: HY-W325699 Purity: 99.41%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

HIV-1 inhibitor-48 (compound 13o) is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity.

For research use only. We do not sell to patients.

HIV-1 inhibitor-48 Chemical Structure

CAS No. : 374067-85-3

Size	Price	Stock	Quantity
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 298	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 470	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

HIV-1 inhibitor-48 (compound 13o) is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity^[1].

Molecular Weight

394.27

Formula

C₁₉H₁₆BrN₅

CAS No.

374067-85-3

Appearance

Solid

Color

White to off-white

SMILES

CC1=C(C(=CC(=C1)Br)C)N=C2C=CN=C(NC3=CC=C(C=C3)C#N)N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (317.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5363 mL	12.6817 mL	25.3633 mL
5 mM	0.5073 mL	2.5363 mL	5.0727 mL
10 mM	0.2536 mL	1.2682 mL	2.5363 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.41%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (244 KB) HNMR (261 KB) LCMS (266 KB)

Handling Instructions (2659 KB)

References

[1]. Ludovici DW, et al. Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2235-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5363 mL	12.6817 mL	25.3633 mL	63.4083 mL
	5 mM	0.5073 mL	2.5363 mL	5.0727 mL	12.6817 mL
	10 mM	0.2536 mL	1.2682 mL	2.5363 mL	6.3408 mL
	15 mM	0.1691 mL	0.8454 mL	1.6909 mL	4.2272 mL
	20 mM	0.1268 mL	0.6341 mL	1.2682 mL	3.1704 mL
	25 mM	0.1015 mL	0.5073 mL	1.0145 mL	2.5363 mL
	30 mM	0.0845 mL	0.4227 mL	0.8454 mL	2.1136 mL
	40 mM	0.0634 mL	0.3170 mL	0.6341 mL	1.5852 mL
	50 mM	0.0507 mL	0.2536 mL	0.5073 mL	1.2682 mL
	60 mM	0.0423 mL	0.2114 mL	0.4227 mL	1.0568 mL
	80 mM	0.0317 mL	0.1585 mL	0.3170 mL	0.7926 mL
	100 mM	0.0254 mL	0.1268 mL	0.2536 mL	0.6341 mL