HIV-1 inhibitor-48
Based on 1 Customer Validation
HIV-1 inhibitor-48 (compound 13o) is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.38%
- No. CAS: 374067-85-3
- Fòrmula: C19H16BrN5
- Peso molecular:394.27
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-131596B
Emtricitabine triphosphate tetrasodium saltEmtricitabine Metabolite -
HY-164201
HIV-1 inhibitor-69HIV-1 Reverse Transcriptase Inhibitor -
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AzddMeC (Standard)Reference Standard -
HY-138561B
EFdA-TP tetrasodiumNucleoside RT Inhibitor
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | IC50 |
>100 μM
Compound: 13o
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Inhibitory activity against 100I strain and 103N strain of HIV-I in MT-4 cells
Inhibitory activity against 100I strain and 103N strain of HIV-I in MT-4 cells
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[PMID: 11527705] |
| MT4 | IC50 |
0.0023 μM
Compound: 13o
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Inhibitory activity against LAI strain of HIV-I in MT-4 cells
Inhibitory activity against LAI strain of HIV-I in MT-4 cells
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[PMID: 11527705] |
| MT4 | IC50 |
0.012 μM
Compound: 13o
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Inhibitory activity against 103N strain of HIV-I in MT-4 cells
Inhibitory activity against 103N strain of HIV-I in MT-4 cells
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[PMID: 11527705] |
| MT4 | IC50 |
0.017 μM
Compound: 13o
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Inhibitory activity against 181C strain of HIV-I in MT-4 cells
Inhibitory activity against 181C strain of HIV-I in MT-4 cells
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[PMID: 11527705] |
| MT4 | IC50 |
0.069 μM
Compound: 13o
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Inhibitory activity against 188L strain of HIV-I in MT-4 cells
Inhibitory activity against 188L strain of HIV-I in MT-4 cells
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[PMID: 11527705] |
| MT4 | IC50 |
0.076 μM
Compound: 13o
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Inhibitory activity against 100I strain of HIV-I in MT-4 cells
Inhibitory activity against 100I strain of HIV-I in MT-4 cells
|
[PMID: 11527705] |
| MT4 | IC50 |
0.15 μM
Compound: 13o
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Inhibitory activity against 103N strain and 181C strain of HIV-I in MT-4 cells
Inhibitory activity against 103N strain and 181C strain of HIV-I in MT-4 cells
|
[PMID: 11527705] |
Chemical Information
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No. CAS 374067-85-3
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Appearance Solid
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Peso molecular 394.27
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Fòrmula C19H16BrN5
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Color White to off-white
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SMILES
CC1=C(C(=CC(=C1)Br)C)N=C2C=CN=C(NC3=CC=C(C=C3)C#N)N2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
In Vitro:
DMSO : 125 mg/mL (317.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5363 mL | 12.6817 mL | 25.3633 mL | 63.4083 mL |
| 5 mM | 0.5073 mL | 2.5363 mL | 5.0727 mL | 12.6817 mL | |
| 10 mM | 0.2536 mL | 1.2682 mL | 2.5363 mL | 6.3408 mL | |
| 15 mM | 0.1691 mL | 0.8454 mL | 1.6909 mL | 4.2272 mL | |
| 20 mM | 0.1268 mL | 0.6341 mL | 1.2682 mL | 3.1704 mL | |
| 25 mM | 0.1015 mL | 0.5073 mL | 1.0145 mL | 2.5363 mL | |
| 30 mM | 0.0845 mL | 0.4227 mL | 0.8454 mL | 2.1136 mL | |
| 40 mM | 0.0634 mL | 0.3170 mL | 0.6341 mL | 1.5852 mL | |
| 50 mM | 0.0507 mL | 0.2536 mL | 0.5073 mL | 1.2682 mL | |
| 60 mM | 0.0423 mL | 0.2114 mL | 0.4227 mL | 1.0568 mL | |
| 80 mM | 0.0317 mL | 0.1585 mL | 0.3170 mL | 0.7926 mL | |
| 100 mM | 0.0254 mL | 0.1268 mL | 0.2536 mL | 0.6341 mL |
HIV-1 inhibitor-48 Related Classifications
HY-W325699 Related Classifications
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