1. Anti-infection
  2. HIV
    Reverse Transcriptase

3'-Azido-3'-deoxy-5-methylcytidine 

Cat. No.: HY-111640
Handling Instructions

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells.

For research use only. We do not sell to patients.

3'-Azido-3'-deoxy-5-methylcytidine Chemical Structure

3'-Azido-3'-deoxy-5-methylcytidine Chemical Structure

CAS No. : 1282040-14-5

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1].

IC50 & Target[1]

HIV-1

0.06 μM (EC50, in PBM cells)

XMRV

43.5 μM (CC50, in MCF-7 cells)

References
Molecular Weight

282.26

Formula

C₁₀H₁₄N₆O₄

CAS No.

1282040-14-5

SMILES

OC[[email protected]@H]1[[email protected]@H](N=[N+]=[N-])[[email protected]]([[email protected]](N2C(N=C(C(C)=C2)N)=O)O1)O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
3'-Azido-3'-deoxy-5-methylcytidine
Cat. No.:
HY-111640
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3'-Azido-3'-deoxy-5-methylcytidine

Cat. No.: HY-111640