7-PPD (Synonyms: DMPPD)

Cat. No.: HY-176747 Purity: 98.28%: Data Sheet
COA

SDS
Handling Instructions
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7-PPD (DMPPD) is a rubber antioxidant that scavenges free radicals and inhibits the oxidative degradation of rubber chains. 7-PPD shows promise for research in tire manufacturing and rubber product processing.

For research use only. We do not sell to patients.

7-PPD Chemical Structure

CAS No. : 3081-01-4

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Description

In Vivo

7-PPD (DMPPD) (100-200 mg/kg; injection; twice, 24 hours apart) does not induce a significant increase in micronuclei frequency or alter the P/N ratio in mouse bone marrow erythrocytes^[1].
7-PPD (DMPPD) (100-200 mg/kg; i.p.; twice, 24 hours apart) does not induce a significant increase in chromosomal abnormalities in mouse bone marrow cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Inbred Swiss albino (male, 8-10 weeks old)^[1]
Dosage:	100, 150, 200 mg/kg
Administration:	injection; twice, 24 hours apart
Result:	Exhibited polychromatic cells with micronuclei at 0.37% (100 mg/kg), 0.37% (150 mg/kg), 0.39 % (200 mg/kg). Exhibited normochromatic cells with micronuclei at 0.12 % (100 mg/kg), 0.13% (150 mg/kg), 0.15% (200 mg/kg).

Molecular Weight

282.42

Formula

C₁₉H₂₆N₂

CAS No.

3081-01-4

Appearance

Solid

Color

Light brown to brown

SMILES

CC(C)CCC(NC1=CC=C(NC2=CC=CC=C2)C=C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 5.33 mg/mL (18.87 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5408 mL	17.7041 mL	35.4083 mL
5 mM	0.7082 mL	3.5408 mL	7.0817 mL
10 mM	0.3541 mL	1.7704 mL	3.5408 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.1%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)

References

[1]. George J, et al. Lack of induction of chromosome aberrations and micronuclei by N-(1,3-dimethylbutyl)-N-phenylparaphenylenediamine in mouse bone marrow cells. Mutat Res. 1996;370(3-4):191-194. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5408 mL	17.7041 mL	35.4083 mL	88.5206 mL
	5 mM	0.7082 mL	3.5408 mL	7.0817 mL	17.7041 mL
	10 mM	0.3541 mL	1.7704 mL	3.5408 mL	8.8521 mL
	15 mM	0.2361 mL	1.1803 mL	2.3606 mL	5.9014 mL

7-PPD Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-PPD3081-01-4DMPPDReactive Oxygen Species (ROS)Swiss albino mouse bone marrow cellsSalmonella typhimurium (TA98)chromosome aberrationspolychromatic erythrocytesmouse bone marrow erythrocytesInhibitorinhibitorinhibit

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7-PPD (Synonyms: DMPPD)

7-PPD Related Antibodies

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