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Results for "

6,6',6

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (635) Cardiovascular Disease (104) Endocrinology (78) Infection (221) Inflammation/Immunology (717) Metabolic Disease (276) Neurological Disease (320)
Click Chemistry:	ADC Synthesis (2) Labeling and Fluorescence Imaging (2) PROTAC Synthesis (1) Azide (17) Alkynes (11)
Oligonucleotides:	Adenosine (1) Thickeners (2) Inosine Nucleoside (1) Guanosine (3) Nucleotide Analogs (4) mRNA (1) Phospholipids (5) Freeze-drying Protective Agents (1) Antisense Oligonucleotides (1) Other Phosphoramidite (3) Guanine (2) Fluorescent Dye Phosphoramidite (2) Aptamers (4) Nucleoside Analogs (14) CpG ODNs (11) Uridine (2) Emulsifiers (3) Inosine (2) Cationic Lipids (3) Phosphoramidites (7)

2337

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

132

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

550

Natural
Products

Recombinant Proteins

178

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-50663

MK 0893 5+ Cited Publications	GCGR	Metabolic Disease
MK 0893 is a potent and selective glucagon receptor antagonist with an IC₅₀ of 6.6 nM.

HY-112137

*Trehalose-6,6'-dibehenate*	Caspase Interleukin Related MyD88	Inflammation/Immunology
Trehalose-6,6'-dibehenate is an orally active glycolipid. Trehalose-6,6'-dibehenate activates Mincle and inflammasome, inducing IL-1β secretion in a caspase activity-dependent manner. Trehalose-6,6'-dibehenate exerts a Myd88-dependent adjuvant activity. Trehalose-6,6'-dibehenate induces Th-1/Th-17 immune responses .

HY-11027

MK-0773 4 Publications Verification PF-05314882	Androgen Receptor	Endocrinology
MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC₅₀ of 6.6 nM.

HY-B1382

Pempidine 1,2,2,6,6-Pentamethylpiperidine	nAChR	Cardiovascular Disease Neurological Disease
Pempidine (1,2,2,6,6-Pentamethylpiperidine) is an orally active ganglionic blocking agent used in hypertension-related conditions. Pempidine is a nicotinic receptor blocker. Pempidine can antagonize the nicotine-induced increase of the striatal dopamine (DA) in vitro .

HY-W145657

*Trehalose 6,6′-dimycolate* Cord Factor	Biochemical Assay Reagents	Infection
Trehalose 6,6'-dimycolate (Cord Factor) is trehalose 6,6'-dimycolate, a cell wall glycolipid of Mycobacterium tuberculosis, which can be used to simulate inflammation and granuloma induced by Mycobacterium tuberculosis (MTB) form. Trehalose 6,6′-dimycolate also protects Mycobacterium tuberculosis from macrophage-mediated killing, inhibits efficient antigen presentation, and reduces the development of protective T cell responses .

HY-N1131

Triacetonamine 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone	Others	Metabolic Disease
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-N11729

*Pyrogallol-phloroglucinol-6,6-bieckol*	Others	Others
Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia .

HY-157914

Dibenzyl-14-crown-4 6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane	Biochemical Assay Reagents	Others
Dibenzyl-14-crown-4 (6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane) is a crown ether derivate, which serves as neutral carrier in PVC ion-selective electrode, improves the Li ⁺ selectivity against Na ⁺ and K ⁺ .

HY-N1131A

Triacetonamine hydrochloride 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone hydrochloride	Drug Intermediate	Metabolic Disease
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) hydrochloride is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .

HY-W456433

6,6'-Di-tert-butyl-2,2'-bipyridine	MOFs	Others
6,6'-Di-tert-butyl-2,2'-bipyridine (6,6'-di(tert-butyl)-2,2'-bipyridine) is a metal-organic framework (MOF).

HY-W273281

6,6′-Dithiodinicotinic acid	MOFs	Others
6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker .

HY-W080797

*4,4,5,5,6,6,6-Heptafluorohexanoic acid* 3:3 FTCA	Biochemical Assay Reagents	Others
4,4,5,5,6,6,6-Heptafluorohexanoic acid (3:3 FTCA) is a polyfluoroalkyl substance (PFAS) that accumulate in the environment. 3:3 FTCA binds to many proteins, including the primary human serum transport protein albumin (HSA) .

HY-N1131B

Triacetonamine monohydrate 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone monohydrate	Others	Metabolic Disease
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .

HY-W451242

*1-Methylpiperazine-2,2,3,3,5,5,6,6-d8* 1-Methylpiperazine-d₈ （Dihydrochloride）	Isotope-Labeled Compounds	Others
1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ .

HY-W004545

6,6'-Dimethyl-2,2'-bipyridyl 6,6'-Dimethyl-2,2'-bipyridine	MOFs	Others
6,6'-Dimethyl-2,2'-bipyridyl (6,6'-Dimethyl-2,2'-bipyridine) is a metal-organic framework (MOF).

HY-N15932

C6(6-Azido) LacCer	Biochemical Assay Reagents	Others
C6(6-Azido) LacCer is a clickable sphingolipid.

HY-N11728

*2,7"-Phloroglucinol-6,6'-bieckol*	Amylases Glycosidase	Metabolic Disease
2,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC₅₀ values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research .

HY-W585822

*Disodium 6,6′-oxybis(2-naphthalenesulfonate)*	Drug Intermediate	Others
Disodium 6,6′-oxybis(2-naphthalenesulfonate) is an impurity of Sunset Yellow FCF (HY-D0249). Disodium 6,6′-oxybis(2-naphthalenesulfonate) acts as a surfactant, emulsifier, and dispersant. The compound has found applications in synthesizing polymers, pharmaceuticals, and agrochemicals.

HY-178333

HDAC6-IN-66	HDAC	Cancer
HDAC6-IN-66 is a potent and selective histone deacetylase (HDAC) 6 inhibitor with an IC₅₀ of 1.8 nM. HDAC6-IN-66 induces α-tubulin acetylation over histone H3. HDAC6-IN-66 can be used for the research of cancer .

HY-110085

*2,2′-Dihydroxy-6,6′-dinaphthyl disulfide* DDD; Bis(6-hydroxy-2-naphthyl)disulfide; PIR-3.5	PAK	Cancer
2,2′-Dihydroxy-6,6′-dinaphthyl disulfide (PIR-3.5) is a PAK1 inhibitor .

HY-W341363R

*1-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-2-en-1-one (Standard)* 4-(2,6,6-Trimethyl cyclohex-2-enyl)-but-2-en-4-one (Standard)	Reference Standards
1-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-2-en-1-one (Standard) is the analytical standard of 1-(2,6,6-Trimethylcyclohex-2-en-1-yl)but-2-en-1-one. This product is intended for research and analytical applications.

HY-N11975

*Glycyrrhizin-6′,6′′-dimethylester*	Others	Others
Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .

HY-N15961

C6(6-Azido) GalCer	Biochemical Assay Reagents	Others
C6(6-Azido) GalCer is a clickable sphingolipid.

HY-159471

N6-[(6-Aminohexyl)carbamoylmethyl]-ADP	Drug Derivative	Others
N6-[(6-Aminohexyl)carbamoylmethyl]-ADP is an analog of ADP (HY-W010918), which can be obtained by alkylating ADP .

HY-W748961

*Norethindrone Acetate-2,2,4,6,6,10-d6*	Isotope-Labeled Compounds	Others
Norethindrone Acetate-2,2,4,6,6,10-d₆ is deuterated labeled Norethindrone Acetate-2,2,4,6,6,10.

HY-151870S

*(±)-trans-4-Hydroxy-2-hexenal-5,5,6,6,6-d5 Dimethyl Acetal*	Isotope-Labeled Compounds	Others
(±)-trans-4-Hydroxy-2-hexenal-5,5,6,6,6-dd₅ Dimethyl Acetal is the deuterium labeled (±)-trans-4-Hydroxy-2-hexenal Dimethyl Acetal .

HY-W013113S

*Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d24* Sebacic acid bis(2,2,6,6-tetramethyl-4-piperidyl) ester-d₂₄	Isotope-Labeled Compounds	Others
Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d₂₄ (Sebacic acid bis(2,2,6,6-tetramethyl-4-piperidyl) ester-d₂₄) is deuterium labeled BTMPS .

HY-151078S

*2,3′,5-Trichlorobiphenyl-2′,3,4,4′,6,6′-d6*	Isotope-Labeled Compounds	Others
2,3′,5-Trichlorobiphenyl-2′,3,4,4′,6,6′-d₆ is the deuterium labeled 2,3′,5-Trichlorobiphenyl .

HY-W048972

*2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol*	Endogenous Metabolite	Others
2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is isolated from Chrysanthemum indicum L. .

HY-N10906

*(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one*	Others	Others
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone .

HY-Y1754

*2,2,6,6-Tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid* TOAC	Biochemical Assay Reagents
2,2,6,6-Tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid (TOAC) is a compound with the ability to probe conformational changes, folding processes and interactions of peptides and proteins. 2,2,6,6-Tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid is often used in relevant biological research to gain a deeper understanding of the behavior and function of biomacromolecules. 2,2,6,6-Tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid plays an important role in analyzing the interactions and dynamic responses of biological systems.

HY-B1382A

Pempidine hydrochloride 1,2,2,6,6-Pentamethylpiperidine hydrochloride	nAChR	Cardiovascular Disease Neurological Disease
Pempidine (1,2,2,6,6-Pentamethylpiperidine) hydrochloride is an orally active ganglionic blocking agent used in the treatment of hypertension. Pempidine hydrochloride blocks the effects of intravenously administered addictive drugs and peripheral vagal nerve stimulation on blood pressure, and reduces the output of acetylcholine .

HY-W130266R

*2,2,4,4,6,6-Hexamethyl-1,3,5,2,4,6-trioxatrisilinane (Standard)* Hexamethylcyclotrisiloxane (Standard)	Reference Standards
2,2,4,4,6,6-Hexamethyl-1,3,5,2,4,6-trioxatrisilinane (Standard) is the analytical standard of 2,2,4,4,6,6-Hexamethyl-1,3,5,2,4,6-trioxatrisilinane. This product is intended for research and analytical applications.

HY-N9193

*2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone*	Biochemical Assay Reagents	Others
2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone is an isoflavone .

HY-150999S

*2,2′,5-Trichlorobiphenyl-3,4,4′,6,6′-d5*	Isotope-Labeled Compounds	Others
2,2′,5-Trichlorobiphenyl-3,4,4′,6,6′-d₅ is the deuterium labeled 2,2′,5-Trichlorobiphenyl .

HY-W129420S

*N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d24*	Isotope-Labeled Compounds	Others
N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d₂₄ is deuterium labeled N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide) .

HY-163137

Telomerase-IN-6	Telomerase	Cancer
Telomerase-IN-6（6f）is a telomerase inhibitor with antitumor activity .

HY-W129474R

*Poly(4-hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol-alt-1,4-butanedioic acid) (Standard)*	Reference Standards
Poly(4-hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol-alt-1,4-butanedioic acid) (Standard) is the analytical standard of Poly(4-hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol-alt-1,4-butanedioic acid). This product is intended for research and analytical applications.

HY-W004578

*2,2'-Bipyridine-6,6'-dicarboxylic Acid* 2,2Bipyridyl-6,6'-dicarboxylic acid	MOFs	Others
2,2'-Bipyridine-6,6'-dicarboxylic Acid (2,2Bipyridyl-6,6'-dicarboxylic acid) is a metal-organic framework (MOF).

HY-W112870

*[2,2'-Binaphthalene]-6,6'-dicarboxylic acid* 2,2'-Binaphthalene-6,6'-dicarboxylic Acid	MOFs	Others
[2,2'-Binaphthalene]-6,6'-dicarboxylic acid (2,2'-Binaphthalene-6,6'-dicarboxylic Acid) is a metal-organic framework (MOF).

HY-W004557

*[2,2'-Bipyridine]-6,6'-dicarbonitrile* 2,2'-Bipyridine-6,6'-dicarbonitrile	MOFs	Others
[2,2'-Bipyridine]-6,6'-dicarbonitrile (2,2'-Bipyridine-6,6'-dicarbonitrile) is a metal-organic framework (MOF).

HY-W036118

*Diethyl [2,2'-bipyridine]-6,6'-dicarboxylate* Ethyl 6-(6-ethoxycarbonylpyridin-2-yl)pyridine-2-carboxylate	MOFs	Others
Diethyl [2,2'-bipyridine]-6,6'-dicarboxylate (Ethyl 6-(6-ethoxycarbonylpyridin-2-yl)pyridine-2-carboxylate) is a metal-organic framework (MOF).

HY-W034942

*Dimethyl 2, 2'-bipyridine-6, 6'-dicarboxylate* Dimethyl-2,2'-bipyridin-6,6'-dicarboxylat	MOFs	Others
Dimethyl 2, 2'-bipyridine-6, 6'-dicarboxylate (Dimethyl-2,2'-bipyridin-6,6'-dicarboxylat) is a metal-organic framework (MOF).

HY-W1121519

6,6′-Trehalose dioleate	Liposome	Metabolic Disease
6,6′-Trehalose dioleate is a glycolipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

HY-N9859

6,6'-Di-O-sinapoylsucrose	Others	Inflammation/Immunology
6,6'-Di-O-sinapoylsucrose is a sucrose ester hat can be found in cynanchum amplexicaule .

HY-W124405

6,6'-Dibromo-[3,3'-biindolinylidene]-2,2'-dione (E)-6,6'-dibromo-[3,3'-biindolinylidene]-2,2'-dione	MOFs	Others
6,6'-Dibromo-[3,3'-biindolinylidene]-2,2'-dione ((E)-6,6'-dibromo-[3,3'-biindolinylidene]-2,2'-dione) is a metal-organic framework (MOF).

HY-W348165

6,6'-Dimethyl-3,3'-bipyridine	MOFs	Others
6,6'-Dimethyl-3,3'-bipyridine is a metal-organic framework (MOF).

HY-W456434

6,6'-Dimethoxy-2,2'-bipyridine	MOFs	Others
6,6'-Dimethoxy-2,2'-bipyridine is a metal-organic framework (MOF).

HY-W998831

6,6'-Diethynyl-2,2'-bipyridine	MOFs	Others
6,6'-Diethynyl-2,2'-bipyridine is a metal-organic framework (MOF).

HY-W543304

*[2,2':6',2''-Terpyridine]-6,6''-dicarboxylicacid*	MOFs	Others
[2,2':6',2''-Terpyridine]-6,6''-dicarboxylicacid is a metal-organic framework (MOF).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0236

6-Aminocaproic acid 4 Publications Verification EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	PAI-1 Plasminogen/Plasmin PROTAC Linkers
6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .

HY-W011184

6-Phosphogluconic acid trisodium	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Structural Classification Arabidopsis thaliana (L.) Heynh. Plants Brassicaceae Saccharides Source Classification	Endogenous Metabolite Drug Derivative
α,α-Trehalose 6-phosphate (Tre6P) potassium is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate potassium is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-W010128

6-(Dimethylamino)purine 6-Dimethylaminopurine; 6-DMAP	Classification of Application Fields Other Diseases Disease Research Fields	CDK DNA/RNA Synthesis Apoptosis
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis) .

HY-N11848

D-Glucosamine 6-phosphate Glucosamine-6-phosphate; D-GlcN-6-P	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Monosaccharides Source Classification	Endogenous Metabolite
D-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). D-Glucosamine 6-phosphate can be used for the research of diabetes mellitus .

HY-N7110

6-Hydroxyflavone 2 Publications Verification	Monophenols Flavonoids Classification of Application Fields Flavones Labiatae Phenols Plants Medicago truncatula Gaertn. Inflammation/Immunology Disease Research Fields Source Classification	Akt ERK JNK GABA Receptor
6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS (HY-D1056) -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin (BHb) glycosylation. 6-Hydroxyflavone has a kidney protective effect. In addition, 6-Hydroxyflavone enhances GABA-induced current through the Benzodiazepine sites of γ-aminobutyric acid (GABA_A) receptors. 6-Hydroxyflavone shows a clear preference for α2 - and α3 - subtypes, which play an anti-anxiety role ^[6].

HY-N10521

6'-Sialyllactose 1 Publications Verification	Polysaccharides Endogenous metabolite Saccharides	Bacterial VEGFR Akt ERK
6'-Sialyllactose promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose promotes the muscle health .

HY-N1131

Triacetonamine 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone	Tribulus terrester Linn. Alkaloids Piperidine Alkaloids Classification of Application Fields Zygophyllaceae Other Diseases Plants Disease Research Fields Source Classification	Others
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-113514

6-Phosphogluconic acid	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-W013549

6-Aminopenicillanic acid 6-APA	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	Drug Metabolite Bacterial
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-N0917

6''-O-Malonylgenistin 1 Publications Verification Malonylgenistin; Genistin malonate	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Drug Metabolite Taste Receptor
6''-O-Malonylgenistin (Malonylgenistin) is a glycosylated isoflavone and metabolite of Genistin (HY-N0595). 6''-O-Malonylgenistin activates hTAS2R39. 6''-O-Malonylgenistin can be used in the research of bitter taste .

HY-14615R

[6]-Gingerol (Standard) 1 Publications Verification (S)-(+)-[6]Gingerol (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Reference Standards AMPK Apoptosis
^[6]-Gingerol (Standard) is the analytical standard of ^[6]-Gingerol. This product is intended for research and analytical applications. ^[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-N4073

6"-O-Malonyldaidzin 1 Publications Verification	Monophenols Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Phenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Others
6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye .

HY-N9404

6-Benzoylheteratisine	Alkaloids Piperidine Alkaloids Structural Classification Ranunculaceae Aconitum carmichaeli Debx. Plants Source Classification	Sodium Channel
6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na ⁺]i, [Ca ²⁺]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge .

HY-Y1125

6-Methyluracil Pseudothymine	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

HY-N2135

Puerarin 6''-O-Xyloside	Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Apoptosis Caspase Bcl-2 Family Tyrosinase
Puerarin 6''-O-Xyloside is one of the major iso-flavones found in P. lobata. Puerarin 6''-O-Xyloside inhibits cancer cells proliferation, induces apoptosis by upregulating cleaved caspase-3, 7, 9, Bax and downregulating Bcl-2 levles and inhibits tumor growth in mice. Puerarin 6''-O-Xyloside has anti-osteoporotic activity in ovariectomized mice. Puerarin 6''-O-Xyloside inhibits mushroom tyrosinase with an IC₅₀ of 513.8 μM. Puerarin 6''-O-Xyloside can be used for the research of human lung carcinoma, osteoporosis, melanosis and melanomar .

HY-N11729

*Pyrogallol-phloroglucinol-6,6-bieckol*	Microorganisms Phenols Polyphenols Source Classification	Others
Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia .

HY-111247

Ro 09-0680	Ketones, Aldehydes, Acids Labiatae Samanea saman (Jacq.) Merr. Plants Source Classification	Others
Ro 09-0680 is a potent inhibitor of rabbit platelet aggregation induced by Collagen with an IC₅₀ of 6.6 μM .

HY-W001996

6-Hydroxynicotinic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Drug Intermediate Bacterial
6-Hydroxynicotinic acid is an intermediate in the oxidation of Nicotinic acid (HY-B0143) by Pseudomonas fluorescens and metabolite. 6-Hydroxynicotinic acid can be isolated from root exudates of Cucumis melo. 6-Hydroxynicotinic acid disrupts the Auxin signaling pathway. 6-Hydroxynicotinic acid inhibits haustoria precursor formation in Phlipanche aegyptiaca .

HY-N4126

6-Demethoxytangeretin 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Flavones Rutaceae Plants Citrus reticulata Blanco Flavonoids other families Inflammation/Immunology Disease Research Fields Source Classification Cancer	Anaplastic lymphoma kinase (ALK) p38 MAPK Interleukin Related ERK JNK JAK STAT Akt
6-Demethoxytangeretin is a flavonoid compound that can be isolated from Citrus reticulata. 6-Demethoxytangeretin has anti-inflammatory and anti-allergic activities and can inhibit the production of *IL-6* and the expression of related genes in human mast cells through the ALK and MAPK pathways. 6-Demethoxytangeretin can promote CRE-mediated transcription in hippocampal neurons .

HY-N9608

6-Ketocholestanol 3β-Hydroxy-5α-cholestan-6-one	Apocynaceae Diospyros virginiana L. Plants Steroids Source Classification	Cytochrome P450
6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes. 6-Ketocholestanol increases the membrane dipole potential .

HY-N2732

6-Prenylapigenin 6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin	Structural Classification Flavonoids Flavones Maclura pomifera (Raf.) Schneid. Plants Moraceae Source Classification	Others
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .

HY-W015815

6-Methylnicotinamide	Alkaloids Neurological Disease Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Methylnicotinamide is a nicotinamide derivative. 6-methylnicotinamide is also an endogenous metabolite and its sudden increase in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages in rat model. 6-Methylnicotinamide can significantly enhance the coordination effect between acylamino and undercoordinated defective Pb ²⁺ cations. 6-Methylnicotinamide results in enhanced efficiency of perovskite solar cells to 24.33% with excellent environmental storage, heat, and light stabilities .

HY-W097625

6-Methoxyflavone	Flavonoids Flavones Thymelaeaceae Plants Pimelea simplex F.Muell. Source Classification	Toll-like Receptor (TLR) MyD88 p38 MAPK NF-κB Heme Oxygenase (HO)
6-Methoxyflavone is an orally active methoxyflavone. 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling. 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway in HeLa cells. 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation. 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice. 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression. 6-Methoxyflavone can be used for the study of cancer, inflammation and neurological diseases .

HY-W002438

6-Hydroxyindole	Structural Classification Alkaloids Monophenols Classification of Application Fields Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Biochemical Assay Reagents Endogenous Metabolite OAT Ferroptosis
6-Hydroxyindole is an orally active, endogenous long-acting OATP1B1 inhibitor. 6-Hydroxyindole does not alter the cell surface expression or subcellular localization of OATP1B1. 6-Hydroxyindole protects cells against Ferroptosis. 6-Hydroxyindole possesses intrinsic radical-trapping antioxidant activity. 6-Hydroxyindole serves as a component of oxidative hair dyes. 6-Hydroxyindole can be used in research related to renal failure and neurodegenerative diseases .

HY-B1259

6-Acetamidohexanoic acid Acexamic acid; 6-Acetamidocaproic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Drug Intermediate
6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer .

HY-W002751

6-Methylsalicylic acid	Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Source Classification	Drug Intermediate
6-Methylsalicylic acid is the secondary metabolite that could be isolated from some fungi. 6-Methylsalicylic acid can be used as building blocks for synthesis of antibacterial and anti-inflammatory agents .

HY-N4070

6"-O-Acetylgenistin	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Other Diseases Phenols Polyphenols Plants Disease Research Fields Isoflavones Source Classification	Others
6"-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6"-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC₅₀ of 10.6 μM .

HY-W011184R

6-Phosphogluconic acid trisodium (Standard)	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.

HY-N11848R

D-Glucosamine 6-phosphate (Standard) Glucosamine-6-phosphate (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Monosaccharides Source Classification	Endogenous Metabolite Reference Standards
D-Glucosamine 6-phosphate (Glucosamine-6-phosphate; D-GlcN-6-P) (Standard) is an analytical standard for D-Glucosamine 6-phosphate. This product is used for research and analytical applications. D-Glucosamine 6-phosphate is a phosphorylated amino sugar synthesized by glutamine fructose-6-phosphate aminotransferase (GFAT). The expression level of D-Glucosamine 6-phosphate is regulated by glucose and glutamine concentrations .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Endogenous metabolite Saccharides Source Classification	Endogenous Metabolite Drug Derivative
α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-W102516

6-Dehydroprogesterone Δ6-Progesterone	Endogenous metabolite Steroids Source Classification	Endogenous Metabolite
6-Dehydroprogesterone (Δ6-Progesterone) is a steroid compound that can be found in Botryodiplodia theobromae. 6-Dehydroprogesterone is a metabolic product of Progesterone (HY-N0437) after a microbial dehydrogenation reaction. 6-Dehydroprogesterone can be used to study steroid metabolism pathways, microbial dehydrogenase activity, and the biotransformation of steroids .

HY-N1131B

Triacetonamine monohydrate 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone monohydrate	Alkaloids Piperidine Alkaloids other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Others
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .

HY-N10800

*1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione*	Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants Source Classification	Others
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .

HY-W001996R

6-Hydroxynicotinic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Drug Intermediate Bacterial
6-Hydroxynicotinic acid (Standard) is the analytical standard of 6-Hydroxynicotinic acid (HY-W001996). This product is intended for research and analytical applications. 6-Hydroxynicotinic acid is an intermediate in the oxidation of Nicotinic acid (HY-B0143) by Pseudomonas fluorescens and metabolite. 6-Hydroxynicotinic acid can be isolated from root exudates of Cucumis melo. 6-Hydroxynicotinic acid disrupts the Auxin signaling pathway. 6-Hydroxynicotinic acid inhibits haustoria precursor formation in Phlipanche aegyptiaca .

HY-102015R

6-Biopterin (Standard) L-Biopterin (Standard)	Structural Classification Natural Products Disease markers Nervous System Disorder Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards NO Synthase
6-Biopterin (Standard) is the analytical standard of 6-Biopterin. This product is intended for research and analytical applications. 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

HY-N11978

6-Hydroxykynurenic acid 6-HKA	Ginkgoaceae Ketones, Aldehydes, Acids Plants Ginkgo biloba Source Classification	iGluR
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC₅₀: 59 μM) .

HY-B0941R

6-Benzylaminopurine (Standard) Benzyladenine (Standard); 6-BAP (Standard); N6-Benzyladenine (Standard)	Structural Classification Natural Products Animals Source Classification	Reference Standards Endogenous Metabolite
6-Benzylaminopurine (Standard) is the analytical standard of 6-Benzylaminopurine. This product is intended for research and analytical applications. 6-Benzylaminopurine (Benzyladenine) is a cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables .

HY-W015815R

6-Methylnicotinamide (Standard)	Alkaloids Pyridine Alkaloids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
6-Methylnicotinamide is a nicotinamide derivative. 6-methylnicotinamide is also an endogenous metabolite and its sudden increase in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages in rat model. 6-Methylnicotinamide can significantly enhance the coordination effect between acylamino and undercoordinated defective Pb2+ cations. 6-Methylnicotinamide results in enhanced efficiency of perovskite solar cells to 24.33% with excellent environmental storage, heat, and light stabilities .

HY-W028263

6-Hydroxyflavanone	Flavonoids Flavonones Muntingia calabura L. Plants Muntingiaceae Source Classification	COX Opioid Receptor GABA Receptor Lipoxygenase
6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes .

HY-N15932

C6(6-Azido) LacCer	Lipid	Biochemical Assay Reagents
C6(6-Azido) LacCer is a clickable sphingolipid.

HY-N11728

*2,7"-Phloroglucinol-6,6'-bieckol*	Microorganisms Phenols Polyphenols Source Classification	Amylases Glycosidase
2,7"-Phloroglucinol-6,6'-bieckol is an orally active dual α-amylase/α-glucosidase inhibitor with IC₅₀ values of 6.94 μM and 23.35 μM respectively. 2,7"-Phloroglucinol-6, 6'-bieckol alleviates postprandial hyperglycemia in diabetic mice. 2,7"-Phloroglucinol-6,6'-bieckol can be used in diabetes research .

HY-W013549R

6-Aminopenicillanic acid (Standard) 6-APA (Standard)	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Drug Metabolite Reference Standards Bacterial
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

HY-13677R

6-Mercaptopurine (Standard) Mercaptopurine (Standard); 6-MP (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite
6-Mercaptopurine (Standard) is the analytical standard of 6-Mercaptopurine. This product is intended for research and analytical applications. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.

HY-N10699

6-Methoxykaempferol	Flavonols Flavonoids Animals Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification Cancer	Others
6-Methoxykaempferol is a flavone that can be found in brazilian propolis. 6-Methoxykaempferol shows anti-proliferative activity for cancer cells .

HY-129529

6-Hydroxyluteolin 7-glucoside	Flavonoids Classification of Application Fields Flavones Phenols Polyphenols Plants Compositae Euchresta formosana (Hayata) Ohwi Inflammation/Immunology Disease Research Fields Source Classification	Others
6-Hydroxyluteolin 7-glucoside is a glycoside. 6-Hydroxyluteolin 7-glucoside can be isolated from Tanacetum vulgare and C. chrvsanthus cv. Cream Beauty. 6-Hydroxyluteolin 7-glucoside can be used in inflammation research .

HY-N2720

6-O-Caffeoylarbutin Robustaside B	Structural Classification Classification of Application Fields Simple Phenylpropanols Phenols Polyphenols Metabolic Disease Phenylpropanoids Ericaceae Plants Disease Research Fields Source Classification Vaccinium dunalianum Wight	PI3K Reactive Oxygen Species (ROS)
6-O-Caffeoylarbutin (Robustaside B) possesses antioxidant activity . 6-O-Caffeoylarbutin ameliorates neurological functions and deficits in ischemic mice.

HY-N10802

6-O-Isobutyrylbritannilactone	Terpenoids Orchidaceae Andira inermis (W.Wright) DC. Plants Compositae Source Classification	ERK Akt PI3K Epigenetic Reader Domain
6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor. 6-O-Isobutyrylbritannilactone, a sesquiterpene, can be isolated from the flowers of Inula britannica. 6-O-Isobutyrylbritannilactone inhibits IBMX (HY-12318)-induced melanin production in B16F10 cells. 6-O-Isobutyrylbritannilactone also regulates ERK, PI3K/AKT, and CREB, shows antimelanogenic activity in zebrafish embryos models .

HY-N6883

6-Methoxytricin	Flavonoids other families Classification of Application Fields Flavones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Aldose Reductase
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC₅₀ values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent .

HY-N11975

*Glycyrrhizin-6′,6′′-dimethylester*	Ketones, Aldehydes, Acids Launaea mucronata (Forssk.) Muschl. Plants Umbelliferae Source Classification	Others
Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .

Cat. No.	Product Name	Chemical Structure

HY-152039S

6PPD-quinone-d5
6PPD-quinone-d₅ is the deuterium labeled 6PPD-quinone .

HY-W454945S

*tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8*
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate .

HY-141626S

6β-Hydroxytestosterone-d7
6β-Hydroxytestosterone-d₇ is a deuterated labeled 6β-Hydroxytestosterone. 6β-Hydroxytestosterone is a major metabolite of Testosterone .

HY-112537S1

D-Glucose 6-Phosphate-13C6 (disodium xhydrate)

D-Glucose 6-Phosphate- ¹³C₆ disodium xhydrate is a ¹³C-labeled D-Glucose 6-phosphate disodium xhydrate. D-Glucose 6-phosphate disodium xhydrate is a key central node metabolite in sugar metabolism, serving as the initial metabolite of glycolysis and pentose phosphate pathway, and also a substrate for glycogen synthesis. D-Glucose 6-phosphate disodium xhydrate can act as a metabolic stress signal, especially when phosphoglucomutase (PGI) is inhibited, activating the mTOR pathway, promoting protein synthesis, and thereby participating in the remodeling process of the heart. D-Glucose 6-phosphate disodium xhydrate can be used in research related to non-insulin-dependent diabetes and heart failure.

HY-W587724S

6β-Hydroxy Cortisol-d4
6β-Hydroxy Cortisol-d₄ is a deuterium labeled compound.

HY-113358S

6-keto Prostaglandin F1α-d4
6-keto Prostaglandin F1α-d₄ is the deuterium labeled 6-keto Prostaglandin F1α .

HY-125348S

6α-Hydroxy Paclitaxel-d5

6α-Hydroxy Paclitaxel-d₅ is the deuterium labeled 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel is one of the main metabolites of Paclitaxel (PTX) (HY-B0015), and it is generated by the liver cytochrome P450 enzyme CYP2C8. 6α-Hydroxy paclitaxel has bone marrow toxicity, but it can enhance the cytotoxicity of PTX against leukemia cells without causing cell toxicity. 6α-Hydroxy paclitaxel can be used in leukemia research.

HY-N1131S

Triacetonamine-d17
Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-152039S1

6PPD-Q-13C6
6PPD-quinone- ¹³C₆ is the ¹³C labeled 6PPD-quinone .

HY-108229S

6β-Naltrexol-d3
6β-Naltrexol-d₃ (6β-Hydroxynaltrexone-d₃) is deuterium labeled 6β-Naltrexol. 6β-Naltrexol (6β-Hydroxynaltrexone), the primary metabolite of Naltrexone, is a peripherally selective opioid antagonist. 6β-Naltrexol selectively inhibits gastrointestinal opioid effects in human subjects and inhibits Morphine-induced slowing of gastrointestinal transit .

HY-13677S1

6-Mercaptopurine-13C2,15N
6-Mercaptopurine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

HY-112537S2

D-Glucose 6-phosphate-13C

D-Glucose 6-phosphate- ¹³C is ¹³C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure.

HY-B0152S4

Adenine-15N5

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅; Vitamin B4- ¹⁵N₅) is ¹⁵N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-B0236S

6-Aminocaproic acid-d6

6-Aminocaproic acid-d₆ is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .

HY-142117S

6-Sulfatoxy Melatonin-d4 sodium
6-Sulfatoxy Melatonin-d4 sodium is the deuterium labeled 6-Sulfatoxy Melatonin sodium .

HY-132425S

6-Hydroxy Melatonin-d4
6-Hydroxy Melatonin-d₄ is the deuterium labeled 6-Hydroxy Melatonin .

HY-W451242

*1-Methylpiperazine-2,2,3,3,5,5,6,6-d8*
1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d₈ .

HY-B0941S

6-Benzylaminopurine-d5
6-Benzylaminopurine-d₅ is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin .

HY-137315S

TML-6-d3
TML-6-d₃ is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-

HY-13677S

6-Mercaptopurine-d2
6-Mercaptopurine-d₂ is the deuterium labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent .

HY-B0152S7

Adenine-15N5 hydrochloride hydrate

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅) hydrochloride hydrate is the ¹⁵N-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W002004S1

4-Amino-TEMPO-d17

4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W741297

6a-Hydroxy Testosterone-d3
6a-Hydroxy Testosterone-d₃ is the deuterium labeled 6a-Hydroxy Testosterone.

HY-142117S1

6-Sulfatoxy Melatonin-d4
6-Sulfatoxy Melatonin-d₄ is deuterium labeled 6-Sulfatoxy Melatonin.

HY-102015S

6-Biopterin-d3
6-Biopterin-d₃ (L-Biopterin-d₃) is deuterium labeled 6-Biopterin. 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor .

HY-W013591S

6-O-Methyl-guanine-d3
6-O-Methyl-guanine-d₃ is the deuterium labeled 6-O-Methyl-guanine .

HY-W748961

*Norethindrone Acetate-2,2,4,6,6,10-d6*
Norethindrone Acetate-2,2,4,6,6,10-d₆ is deuterated labeled Norethindrone Acetate-2,2,4,6,6,10.

HY-151870S

*(±)-trans-4-Hydroxy-2-hexenal-5,5,6,6,6-d5 Dimethyl Acetal*
(±)-trans-4-Hydroxy-2-hexenal-5,5,6,6,6-dd₅ Dimethyl Acetal is the deuterium labeled (±)-trans-4-Hydroxy-2-hexenal Dimethyl Acetal .

HY-W013113S

*Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d24*
Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d₂₄ (Sebacic acid bis(2,2,6,6-tetramethyl-4-piperidyl) ester-d₂₄) is deuterium labeled BTMPS .

HY-151078S

*2,3′,5-Trichlorobiphenyl-2′,3,4,4′,6,6′-d6*
2,3′,5-Trichlorobiphenyl-2′,3,4,4′,6,6′-d₆ is the deuterium labeled 2,3′,5-Trichlorobiphenyl .

HY-150999S

*2,2′,5-Trichlorobiphenyl-3,4,4′,6,6′-d5*
2,2′,5-Trichlorobiphenyl-3,4,4′,6,6′-d₅ is the deuterium labeled 2,2′,5-Trichlorobiphenyl .

HY-W129420S

*N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d24*
N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d₂₄ is deuterium labeled N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide) .

HY-W002004S

4-Amino-TEMPO-d17,15N

4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W777751

6-Desamino 6-chloro etravirine-13C3
6-Desamino 6-chloro etravirine- ¹³C₃ is the ¹³C-labeled 6-Desamino 6-Chloro Etravirine (HY-W740641).

HY-B0236S1

6-Aminocaproic acid-d10

6-Aminocaproic acid-d₁₀ is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .

HY-W701541

6-Aminocaproic acid-d10 hydrochloride

6-Aminocaproic acid-d₁₀ hydrochloride (EACA-d₁₀ hydrochloride; Epsilon-Amino-n-caproic Acid-d₁₀ hydrochloride; 6-Aminohexanoic acid-d₁₀ hydrochloride) is the deuterium labeled 6-Aminocaproic acid hydrochloride (HY-B0236A). 6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .

HY-W654206

D-Glucose 6-Phosphate Sodium Salt Hydrate-13C6
D-Glucose 6-Phosphate Sodium Salt Hydrate- ¹³C₆ is the ¹³C-labeled D-Glucose 6-Phosphate Sodium Salt Hydrate.

HY-132437S

6-Hydroxy Bentazon-d7
6-Hydroxy Bentazon-d₇ is the deuterium labeled 6-Hydroxy Bentazon .

HY-W740771

6α-Hydroxy cortisol-d4
6α-Hydroxy cortisol-d₄ is the deuterium labeled 6α-Hydroxy cortisol.

HY-133925S1

6-O-Desmethyl donepezil-d5 hydrochloride
6-O-Desmethyl donepezil-d₅ (hydrochloride) is deuterium labeled 6-O-Desmethyl donepezil.

HY-133925S2

6-O-Desmethyl donepezil-d7
6-O-Desmethyl donepezil-d₇ is deuterated labeled 6-O-Desmethyl donepezil.

HY-W198678S

6-Methylthioguanine-13C,d3
6-Methylthioguanine- ¹³C,d₃ is the ¹³C labeled 6-Methylthioguanine .

HY-133925S

6-O-Desmethyl donepezil-d5
6-O-Desmethyl donepezil-d₅ is the deuterium labeled 6-O-Desmethyl donepezil .

HY-W097453S

6-(Methylthio)purine-13C,d3
6-(Methylthio)purine- ¹³C,d₃ is the ¹³C labeled 6-(Methylthio)purine.

HY-W588292S

6α-Methylprednisolone 17-propionate-d6
6α-Methylprednisolone 17-propionate-d6 is the deuterium labeled 6α-Methylprednisolone 17-propionate .

HY-B1110S

Nomifensine-d3 maleate

Nomifensine-d₃ ((±)-Nomifensine-d₃) maleate is the deuterium labeled Nomifensine maleate (HY-B1110A). Nomifensine ((±)-Nomifensine) maleate is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine maleate inhibits uptake of NE, DA and 5-HT in rat brain synaptosomes, with IC₅₀ values of 6.6 nM, 48 nM and 830 nM, and K_i values of 4.7 nM, 26 nM and 4000 nM, respectively. Nomifensine maleate has antidepressant and analgesic effects. Nomifensine maleate is used in neurodegenerative diseases, compound addiction, and pain research ^[6] .

HY-132558S

6-Desacetyl-6-bromo-N-Boc Palbociclib-d4
6-Desacetyl-6-bromo-N-Boc Palbociclib-d₄ is the deuterium labeled 6-Desacetyl-6-bromo-N-Boc Palbociclib .

HY-W754406

6PPD-Quinone methyl ester-d5
6PPD-Quinone methyl ester-d₅ (Methyl carboxylate 6ppd-quinone-d₅) is the deuterium labeled 6PPD-Quinone methyl ester.

HY-W726311

6-Aminoquinoline-d6
6-Aminoquinoline-d₆ is the deuterium labeled 6-Aminoquinoline (HY-W007404). 6-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W016221S1

6-Hydroxy Chlorzoxazone-15N,d2
6-Hydroxy Chlorzoxazone- ¹⁵N,d₂ is the ¹⁵N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221). 6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1402G

Hydrocortisone hemisuccinate Hydrocortisone 21-hemisuccinate	Interleukin Related	Metabolic Disease Inflammation/Immunology Endocrinology
Hydrocortisone hemisuccinate GMP (Hydrocortisone 21-hemisuccinate GMP) is a GMP-grade version of Hydrocortisone hemisuccinate (HY-B1402). GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of *IL-6* and IL-3 with IC₅₀ values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers . .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Ferroptosis Glutathione Peroxidase ACSL Family Amino acid Transporter	Neurological Disease Inflammation/Immunology
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and *IL-6*). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

HY-12292G

IM-12	NF-κB STAT GSK-3 β-catenin Bcr-Abl	Cancer
IM-12 GMP is IM-12 (HY-12292) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IM-12 is an orally active anti-inflammatory agent that targets and inhibits the NF-κB and STAT3 signaling pathways. IM-12 activates the Wnt signaling pathway and promotes the nuclear translocation of β-catenin by inhibiting GSK3β, while also blocking the tyrosine kinase activity of p210BCR/ABL. IM-12 reduces the levels of *IL-6, IL-17, NO, prostaglandin E2, iNOS* and COX-2, and induces ER stress, Ca ²⁺ release, autophagy and apoptosis. IM-12 is heat-sensitive and does not induce autophagy in IM-resistant p210BCR/ABL ^T315I mutant cells. IM-12 is also a component of the 5iLA medium used for naive pluripotent stem cell research. IM-12 has been applied in studies related to carrageenan (HY-125474)-induced hind paw edema, TNBS-induced colitis, and acute and chronic myeloid leukemia .

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