1. Immunology/Inflammation
    GPCR/G Protein
    Apoptosis
  2. Interleukin Related
    Prostaglandin Receptor
    NO Synthase
    Apoptosis
  3. Pectolinarin

Pectolinarin 

Cat. No.: HY-N0314 Purity: 99.89%
Handling Instructions

Pectolinarin possesses anti-inflammatory activity. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway.

For research use only. We do not sell to patients.

Pectolinarin Chemical Structure

Pectolinarin Chemical Structure

CAS No. : 28978-02-1

Size Price Stock Quantity
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
20 mg USD 140 In-stock
Estimated Time of Arrival: December 31
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100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Pectolinarin possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2].

IC50 & Target[2]

IL-6

 

IL-8

 

PGE2

 

In Vitro

Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

622.57

Formula

C29H34O15

CAS No.
SMILES
Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (50.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6062 mL 8.0312 mL 16.0625 mL
5 mM 0.3212 mL 1.6062 mL 3.2125 mL
10 mM 0.1606 mL 0.8031 mL 1.6062 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (3.34 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.34 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.34 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: 99.89%

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Product Name:
Pectolinarin
Cat. No.:
HY-N0314
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