HDAC degrader-1
HDAC6 degrader-6 (compound 10c) is a ByeTAC protein degrader targeting HDAC6, with IC50 values of 0.034 μM, 0.166 μM, 0.703 μM, and 0.293 μM for HDAC6, HDAC1, HDAC2, and HDAC3, respectively. HDAC6 degrader-6 induces cell apoptosis and can be used for the study of multiple myeloma(Blue: USP14 ligand HY-159808; Pink: HDAC ligand HY-176209; Black: linker HY-W016871)
For research use only. We do not sell to patients.
- Formula: C45H63FN6O6
- Molecular Weight:803.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 803.02
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Formula C45H63FN6O6
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SMILES
O=C(NC1=CC=C(CC(NCCCCCCCCCCNC(C2CN(CC(C3=C(C)N(C4=CC=C(F)C=C4)C(C)=C3)=O)CC2)=O)=O)C=C1)CCCCCCC(NO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)