6-Aminopenicillanic acid
Based on 1 Customer Validation
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.
For research use only. We do not sell to patients.
- Purity: 98.49%
- CAS No.: 551-16-6
- Formula: C8H12N2O3S
- Molecular Weight:216.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6-Aminopenicillanic acid (Sodium 6-aminopenicillanate, 0.34-3.4 μmol/mL, 4-5 h) can induce spheroplast formation in Gram-negative bacteria[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 551-16-6
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Appearance Solid
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Molecular Weight 216.26
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Formula C8H12N2O3S
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Color Off-white to light yellow
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SMILES
[C@H]12SC([C@@H](N1C(=O)[C@H]2N)C(=O)O)(C)C
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Synonyms
6-APA
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
0.1 M HCl : 12.5 mg/mL (57.80 mM; ultrasonic and adjust pH to 2 with HCl)
0.1 M NaOH : 5 mg/mL (23.12 mM; Need ultrasonic)
H2O : 0.33 mg/mL (1.53 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O / 0.1 M NaOH / 0.1 M HCl | 1 mM | 4.6241 mL | 23.1203 mL | 46.2406 mL | 115.6016 mL |
| 0.1 M NaOH / 0.1 M HCl | 5 mM | 0.9248 mL | 4.6241 mL | 9.2481 mL | 23.1203 mL |
| 10 mM | 0.4624 mL | 2.3120 mL | 4.6241 mL | 11.5602 mL | |
| 15 mM | 0.3083 mL | 1.5414 mL | 3.0827 mL | 7.7068 mL | |
| 20 mM | 0.2312 mL | 1.1560 mL | 2.3120 mL | 5.7801 mL | |
| 0.1 M HCl | 25 mM | 0.1850 mL | 0.9248 mL | 1.8496 mL | 4.6241 mL |
| 30 mM | 0.1541 mL | 0.7707 mL | 1.5414 mL | 3.8534 mL | |
| 40 mM | 0.1156 mL | 0.5780 mL | 1.1560 mL | 2.8900 mL | |
| 50 mM | 0.0925 mL | 0.4624 mL | 0.9248 mL | 2.3120 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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