1. Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. COX
    Endogenous Metabolite
  3. Lornoxicam

Lornoxicam (Synonyms: Chlortenoxicam; Ro 13-9297)

Cat. No.: HY-B0367 Purity: 98.31%
Handling Instructions

Lornoxicam (Chlortenoxicam), a COX-1 and COX-2 inhibitor, is a new nonsteroidal anti-inflammatory drug (NSAID).

For research use only. We do not sell to patients.

Lornoxicam Chemical Structure

Lornoxicam Chemical Structure

CAS No. : 70374-39-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
200 mg USD 120 In-stock
Estimated Time of Arrival: December 31
500 mg USD 240 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Top Publications Citing Use of Products

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Lornoxicam (Chlortenoxicam), a COX-1 and COX-2 inhibitor, is a new nonsteroidal anti-inflammatory drug (NSAID). Target: COX Lornoxicam showed a balanced inhibition of COX-1/-2 exhibiting the lowest IC50 (0.005 microM/0.008 microM) of the large panel of NSAIDs tested. lornoxicam showed a marked inhibition of IL-6 formation (IC50 54 microM) while the formation ofTNF-alpha, IL-1beta and IL-8 was only moderately affected [1]. Lornoxicam is effective in the treatment of patients with activated osteoarthritis; the analgesic and anti-inflammatory effects of lornoxicam are significantly superior to those of rofecoxib without inferiority in tolerability [2]. Lornoxicam was fully effective for prevention of hyperalgesia [3].

IC50 & Target


5 nM (IC50, in cells)


45 nM (IC50, in cells)

Human Endogenous Metabolite


Clinical Trial
Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.8 mg/mL (10.22 mM; Need ultrasonic and warming)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6895 mL 13.4474 mL 26.8947 mL
5 mM 0.5379 mL 2.6895 mL 5.3789 mL
10 mM 0.2689 mL 1.3447 mL 2.6895 mL
*Please refer to the solubility information to select the appropriate solvent.
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LornoxicamChlortenoxicam Ro 13-9297COXEndogenous MetaboliteCyclooxygenaseInhibitorinhibitorinhibit

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