2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. CXCR2 antagonist 6

CXCR2 antagonist 6 (compound 35c) is a potent CXCR2 antagonist. CXCR2 antagonist 6 shows potent CXCR2 binding affinity (IC50=0.044 µM) and calcium mobilization (IC50=0.66 µM)[ 1].

For research use only. We do not sell to patients.

CXCR2 antagonist 6 Chemical Structure

CXCR2 antagonist 6 Chemical Structure

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CXCR2 antagonist 6 Related Antibodies

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Description

CXCR2 antagonist 6 (compound 35c) is a potent CXCR2 antagonist. CXCR2 antagonist 6 shows potent CXCR2 binding affinity (IC50=0.044 µM) and calcium mobilization (IC50=0.66 µM)[ 1].

IC50 & Target

CXCR2

0.43 μM (IC50)

Molecular Weight

362.40

Formula

C17H16F2N4OS
SMILES

C[C@@H](NC1=C2C=CN=CC2=NC(SCC3=CC=CC(F)=C3F)=N1)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CXCR2 antagonist 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CXCR2 antagonist 6CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsinflammationcancerbinding assaycalcium assayU87 cellsInhibitorinhibitorinhibit

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CXCR2 antagonist 6
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HY-144783
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