2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. 6-O-Senesioyl plenolin

6-O-Senesioyl plenolin is a sesquiterpene lactone found in Centipeda minima with antiallergic activity. 6-O-Senesioyl plenolin inhibits histamine release from mast cells (IC50 = 18 μM) and suppresses pigment exudation in passive cutaneous anaphylaxis tests. 6-O-Senesioyl plenolin can be used in research related to allergy.

For research use only. We do not sell to patients.

6-O-Senesioyl plenolin

6-O-Senesioyl plenolin Chemical Structure

CAS No. : 90042-11-8

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6-O-Senesioyl plenolin Related Antibodies

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Description

6-O-Senesioyl plenolin is a sesquiterpene lactone found in Centipeda minima with antiallergic activity. 6-O-Senesioyl plenolin inhibits histamine release from mast cells (IC50 = 18 μM) and suppresses pigment exudation in passive cutaneous anaphylaxis tests. 6-O-Senesioyl plenolin can be used in research related to allergy[1].

In Vitro

6-O-Senesioyl plenolin (compound 2) inhibits Concanavalin A (HY-P2149)-induced histamine release from rat peritoneal mast cells with an IC50 of 18 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-O-Senesioyl plenolin Related Antibodies
Molecular Weight

346.42

Formula

C20H26O5
CAS No.
SMILES

O(C(C=C(C)C)=O)[C@H]1[C@]2([C@@](C[C@@H](C)[C@]3([C@@]1(C)C(=O)C=C3)[H])(OC(=O)[C@H]2C)[H])[H]
Structure Classification
Initial Source

CENTIPEDA MINIMA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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6-O-Senesioyl plenolin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-O-Senesioyl plenolin90042-11-8Histamine Receptorasthmanasal allergyconcanavalin Arat peritoneal mast cellspassive cutaneous anaphylaxishistamineCentipeda minimamast cellsInhibitorinhibitorinhibit

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6-O-Senesioyl plenolin
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