(6R)-Leucovorin
(6R)-Leucovorin is a derivative of Folic Acid, a vitamin that plays a crucial role in DNA synthesis, DNA repair, and DNA methylation, and also serves as a cofactor in biological reactions involving folate.
For research use only. We do not sell to patients.
- CAS No.: 73951-54-9
- Formula: C20H23N7O7
- Molecular Weight:473.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 73951-54-9
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Molecular Weight 473.44
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Formula C20H23N7O7
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SMILES
O=C(CC[C@H](NC(C1=CC=C(C=C1)NC[C@H]2N(C3=C(NC2)NC(N)=NC3=O)C=O)=O)C(O)=O)O
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Synonyms
(6R)-Folinic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zittoun J, et al. Comparative effect of 6S, 6R and 6RS leucovorin on methotrexate rescue and on modulation of 5-fluorouracil. Br J Cancer. 1991 Jun;63(6):885-8. [Content Brief]
[2]. Liu K, et al. Simultaneous determination of 6R-leucovorin, 6S-leucovorin and 5-methyltetrahydrofolate in human plasma using solid phase extraction and chiral liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Apr 1;877(10):902-10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)