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  4. D-Luciferin 6′-methyl ether

D-Luciferin 6′-methyl ether  (Synonyms: 6′-Methoxyluciferin)

Cat. No.: HY-115749 Purity: 99.93%
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D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site.

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D-Luciferin 6′-methyl ether Chemical Structure

D-Luciferin 6′-methyl ether Chemical Structure

CAS No. : 24404-90-8

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Based on 1 publication(s) in Google Scholar

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Description

D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].

Molecular Weight

294.35

Formula

C12H10N2O3S2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC([C@@H]1N=C(SC1)C(SC2=C3)=NC2=CC=C3OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 11.11 mg/mL (37.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3973 mL 16.9866 mL 33.9732 mL
5 mM 0.6795 mL 3.3973 mL 6.7946 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3973 mL 16.9866 mL 33.9732 mL 84.9329 mL
5 mM 0.6795 mL 3.3973 mL 6.7946 mL 16.9866 mL
10 mM 0.3397 mL 1.6987 mL 3.3973 mL 8.4933 mL
15 mM 0.2265 mL 1.1324 mL 2.2649 mL 5.6622 mL
20 mM 0.1699 mL 0.8493 mL 1.6987 mL 4.2466 mL
25 mM 0.1359 mL 0.6795 mL 1.3589 mL 3.3973 mL
30 mM 0.1132 mL 0.5662 mL 1.1324 mL 2.8311 mL
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D-Luciferin 6′-methyl ether Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Luciferin 6′-methyl ether24404-90-86′-MethoxyluciferinOthersPpyLucD-luciferin analogInhibitorinhibitorinhibit

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