6-O-Methacrylate
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity.
For research use only. We do not sell to patients.
- CAS No.: 950685-51-5
- Formula: C23H30O9
- Molecular Weight:450.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Plasmodium |
Chemical Information
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CAS No. 950685-51-5
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Molecular Weight 450.48
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Formula C23H30O9
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SMILES
C[C@]12[C@@]([C@](O)(CC[C@H]2OC(C)=O)C)([H])[C@@H]([C@]3([H])[C@](OC(C3=C)=O)([H])[C@H]1OC(C)=O)OC(C(C)=C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5. [Content Brief]
[2]. Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-O-Methacrylate Related Classifications
HY-N8521 Related Classifications
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