950685-51-5
Chemical Structure
6-O-Methacrylate
- CAS. Nr.: 950685-51-5
- Formula:C23H30O9
- Molecular Weight:450.48
IUPAC Name: (3aR,4R,4aS,5R,8R,8aR,9S,9aR)-5-hydroxy-4-(methacryloyloxy)-5,8a-dimethyl-3-methylene-2-oxododecahydronaphtho[2,3-b]furan-8,9-diyl diacetate
InChIKey: GDIVEWNXVQCYQL-ZVSMCMQZSA-N
SMILES: C[C@]12[C@@]([C@](O)(CC[C@H]2OC(C)=O)C)([H])[C@@H]([C@]3([H])[C@](OC(C3=C)=O)([H])[C@H]1OC(C)=O)OC(C(C)=C)=O
Biological Activity: 6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
6-O-Methacrylate | 6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5. [Content Brief]
- [2]. Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90. [Content Brief]
