2. Apoptosis Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Apoptosis Reactive Oxygen Species Xanthine Oxidase
  4. 6-Formylpterin

6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells.

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6-Formylpterin Chemical Structure

6-Formylpterin Chemical Structure

CAS No. : 712-30-1

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6-Formylpterin Related Antibodies

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Description

6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1].

In Vitro

6-Formylpterin (2 mM) generats intracellular ROS in HL-60 cells[1].
6-Formylpterin (0.5, 1, and 2 mM, 3 h) increases intracellular H2O2, which induces apoptosis in HL-60 cells and Jurkat cells [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Formylpterin Related Antibodies

Apoptosis Analysis[1]

Cell Line: HL-60 cells, Jurkat cells
Concentration: 0.5, 1, and 2 mM
Incubation Time: 3 h
Result: Induced apoptosis in HL-60 cells[1].
Inhibited Fas-mediated apoptosis in Jurkat cells in 0.5 mM[1].
Molecular Weight

191.15

Formula

C7H5N5O2
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=CC1=CN=C2N=C(N)NC(C2=N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: ≥95.0%

COA (247 KB) HNMR (246 KB) MS (72 KB)

Handling Instructions (2659 KB)
References
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6-Formylpterin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Formylpterin712-30-1ApoptosisReactive Oxygen SpeciesXanthine OxidaseXOCell proliferationHL-60PanC-1Inhibitorinhibitorinhibit

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