COX-2/15-LOX-IN-6
COX-2/15-LOX-IN-6 (Compound 5l) is the dual inhibitor for COX-2 and 15-LOX, with IC50 of 0.201 μM and 11.723 μM. COX-2/15-LOX-IN-6 inhibits the expression of PGE, TNF-α, IL-6 and iNOS in serum, and exhibits anti-inflammatory effect in Carrageenan (HY-125474)-induced rats edema model.
For research use only. We do not sell to patients.
- Formula: C31H28N4O4S
- Molecular Weight:552.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-2 0.201 μM (IC50) |
15-LOX 11.723 μM (IC50) |
Chemical Information
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Molecular Weight 552.64
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Formula C31H28N4O4S
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SMILES
COC1=CC=C(C2=NN(C3=NC(C4=CC=C(OC)C=C4)=CS3)C(C5=CC6=C(C=CC(OC)=C6)N=C5OC)C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2/15-LOX-IN-6 Related Classifications
HY-168340 Related Classifications
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