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CEACAM6 Antibody (YA3992)(PBS only)

(Synonyms: NCA; CEAL; CD66c)

CEACAM6 Antibody (YA3992) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CEACAM6.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, ICC/IF, FC, ELISA

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CEACAM6 Antibody (YA3992)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:25-1:100 1:200-1:400 1:10000

Product Details

Description

CEACAM6 Antibody (YA3992) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CEACAM6.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 37 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 37 kDa
Immunogen

Purified recombinant fragment of human CEACAM6 (AA: 35-256) expressed in HEK293-6e cells supernatant.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CEACAM6 cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells[1][2][3][4][5][6][7].

  • Subcellular Localization

    Cell membrane; Lipid-anchor, GPI-anchor; Apical cell membrane; Cell surface

  • Expression


    Tissue_specificity:Expressed in neutrophils (PubMed:1378450) . Expressed in colonic columnar epithelial cells and goblet cells (PubMed:10436421) . Expressed in various tumor cell lines (protein level) (PubMed:16204051) .

  • Subunit

    Homodimer; homodimerizes via its Ig-like V-type domain. Heterodimer with CEACAM8; heterodimerizes via its Ig-like V-type domain

  • SwissProt ID

    P40199

  • Gene ID
    4680 [NCBI]
  • Synonyms

    NCA; CEAL; CD66c

CEACAM6 Antibody (YA3992)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CEACAM6 Antibody (YA3992)(PBS only) Product Image