2-Deoxy-D-glucose 6-phosphate disodium

Name: 2-Deoxy-D-glucose 6-phosphate disodium
Brand: MedChemExpress
SKU: HY-139409A
Rating: 4.5 (1 reviews)

Cat. No.: HY-139409A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

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2-Deoxy-D-glucose 6-phosphate disodium Chemical Structure

CAS No. : 33068-19-8

Size	Price	Stock	Quantity
5 mg	USD 96	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 290	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 2-Deoxy-D-glucose 6-phosphate disodium:

2-Deoxy-D-glucose 6-phosphate Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

288.10

Formula

C₆H₁₁Na₂O₈P

CAS No.

33068-19-8

Appearance

Solid

Color

White to off-white

SMILES

O=P(O[Na])(O[Na])OC[C@@H](O)[C@@H](O)[C@H](O)CC=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (867.75 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4710 mL	17.3551 mL	34.7102 mL
5 mM	0.6942 mL	3.4710 mL	6.9420 mL
10 mM	0.3471 mL	1.7355 mL	3.4710 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (248 KB) HNMR (271 KB) MS (193 KB)

Handling Instructions (2659 KB)

References

[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [Content Brief]

[2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.4710 mL	17.3551 mL	34.7102 mL	86.7754 mL
	5 mM	0.6942 mL	3.4710 mL	6.9420 mL	17.3551 mL
	10 mM	0.3471 mL	1.7355 mL	3.4710 mL	8.6775 mL
	15 mM	0.2314 mL	1.1570 mL	2.3140 mL	5.7850 mL
	20 mM	0.1736 mL	0.8678 mL	1.7355 mL	4.3388 mL
	25 mM	0.1388 mL	0.6942 mL	1.3884 mL	3.4710 mL
	30 mM	0.1157 mL	0.5785 mL	1.1570 mL	2.8925 mL
	40 mM	0.0868 mL	0.4339 mL	0.8678 mL	2.1694 mL
	50 mM	0.0694 mL	0.3471 mL	0.6942 mL	1.7355 mL
	60 mM	0.0579 mL	0.2893 mL	0.5785 mL	1.4463 mL
	80 mM	0.0434 mL	0.2169 mL	0.4339 mL	1.0847 mL
	100 mM	0.0347 mL	0.1736 mL	0.3471 mL	0.8678 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.