2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Apoptosis NF-κB Keap1-Nrf2 Reactive Oxygen Species
  4. Antioxidant agent-5

Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway.

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Antioxidant agent-5 Chemical Structure

Antioxidant agent-5 Chemical Structure

CAS No. : 2684291-60-7

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Antioxidant agent-5 Related Antibodies

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Description

Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway[1].

Molecular Weight

412.49

Formula

C24H24N6O
CAS No.
SMILES

N#CC1=CC=C(C=C1)CN2CCN(CC2)CC3=NOC(CC4=CNC5=CC=CC=C45)=N3
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Antioxidant agent-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antioxidant agent-52684291-60-7Antioxidant agent5Antioxidant agent 5ApoptosisNF-κBKeap1-Nrf2Reactive Oxygen SpeciesNuclear factor-κBNuclear factor-kappaBVECsPhidiandineIndole-1,2,4-oxadiazoleoxLDLVascular endothelial cellNrf2atherosclerosisInhibitorinhibitorinhibit

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