Keap1-Nrf2-IN-27
Keap1-Nrf2-IN-27 (compound 1C) is a inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) with KD2 value of 0.119 μM. Keap1-Nrf2-IN-27 suppresses the expression of pro-inflammatory cytokine TNF-α and IL-6 in the LPS-induced RAW264.7 cell model.
For research use only. We do not sell to patients.
- Formula: C31H29N5O10S2
- Molecular Weight:695.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 695.72
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Formula C31H29N5O10S2
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SMILES
O=C(O)/C=C\C(NC1=CC=C(S(=O)(N(CC(N)=O)C2=C3C=CC=CC3=C(N(CC(N)=O)S(=O)(C4=CC=C(OC)C=C4)=O)C=C2)=O)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)