1. Membrane Transporter/Ion Channel
  2. HCN Channel
  3. HCN2 modulator-6

HCN2 modulator-6 is a HCN2 ion channel inhibitor has an IC50 of 7 nM. HCN2 modulator-6 inhibits HCN2 ion channel activity. HCN2 modulator-6 can be used for the research of pain, inflammatory pain, neuropathic pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders.

For research use only. We do not sell to patients.

HCN2 modulator-6

HCN2 modulator-6 Chemical Structure

CAS No. : 3080809-10-2

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Description

HCN2 modulator-6 is a HCN2 ion channel inhibitor has an IC50 of 7 nM. HCN2 modulator-6 inhibits HCN2 ion channel activity. HCN2 modulator-6 can be used for the research of pain, inflammatory pain, neuropathic pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders[1].

In Vitro

HCN2 modulator-6 (example 46) has IC50 values of 11990 and 704 nM for HCN1 and HCN4[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

455.46

Formula

C21H18FN5O4S

CAS No.
SMILES

O=C(C1=CC=NS1)NC2=NN(CC(C)OC)C3=NC=C(C4=CC5=C(OCO5)C(F)=C4)C=C23

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HCN2 modulator-6
Cat. No.:
HY-186060
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