IL-17-IN-6
IL-17-IN-6 is a IL-17 inhibitor with a pIC50 of 7.6 against human targets. IL-17-IN-6 binds to IL-17A and blocks downstream pro-inflammatory signaling pathways. IL-17-IN-6 inhibits the release of IL-6 from normal human skin fibroblasts stimulated by IL-17A and TNF. IL-17-IN-6 can be used for research on inflammatory and autoimmune diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C26H26F3N7O3
- 分子量:541.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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IL-17 7.6 (pIC50) |
IL-17-IN-6 (Compound 28) (up to 10 μM; pre-incubated for 30 min, followed by 24 h of cell incubation) potently inhibits IL-17A-mediated IL-6 production in normal human skin fibroblasts, with a cellular pIC50 value of 7.6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 541.52
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分子式 C26H26F3N7O3
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SMILES
O=C(C1=CC=C(C=C1N(CC2=NNC([C@H](C3CCC(CC3)(F)F)NC(/C(F)=C\C4CC4)=O)=N2)C5=O)C#N)N5C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
IL-17-IN-6 関連分類
HY-181826 関連分類
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