6-Benzylthioinosine
6-Benzylthioinosine is a compound with antileukemic activity that increases cytotoxicity against acute myeloid leukemia cells when combined with metformin, modulating cellular metabolism and signaling pathways through multiple mechanisms.
For research use only. We do not sell to patients.
- CAS No.: 6165-03-3
- Formula: C17H18N4O4S
- Molecular Weight:374.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 6165-03-3
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Molecular Weight 374.41
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Formula C17H18N4O4S
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C(N=CN=C32)SCC4=CC=CC=C4)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gupte A, et al. 6-Benzylthioinosine analogues: promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es). Biochem Pharmacol. 2005 Dec 19;71(1-2):69-73. [Content Brief]
[2]. Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-Benzylthioinosine Related Classifications
HY-123718 Related Classifications
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