2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Flow Cytometry Antibodies
  5. PGRMC1 Antibody (YA6966)

PGRMC1 Antibody (YA6966)

製品番号: HY-P87283
User Guide for Antibodies Technical Support

PGRMC1 Antibody (YA6966) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PGRMC1.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 価格（税別） 在庫状況
20 μL $115 見積もりとリードタイムを求めるのご確認
50 μL $185 見積もりとリードタイムを求めるのご確認
100 μL $300 見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

PGRMC1 Antibody (YA6966) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PGRMC1.
Host

Mouse
Clonality

Monoclonal
分子量
Predicted band size: 21.7kDa;
Observed band size: 21.7kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Immunogen

Purified recombinant fragment of human PGRMC1 (AA: 1-195) expressed in E. Coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:200-1:1000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:200-1:1000
FC
FC: Flow Cytometry
1:200-1:400
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Sensitivity Endogenous 純度 Protein A affinity purified.
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in in PBS with 0.05% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity). Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins (PubMed:27599036). Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (PubMed:30443021)
Subcellular Localization：Microsome membrane,Smooth endoplasmic reticulum membrane,Mitochondrion outer membrane,Secreted
Expression：
Tissue_Specificity: Detected in urine (at protein level) (PubMed:36213313, PubMed:37453717). Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472). Widely expressed, with highest expression in liver and kidney
Isoforms & Post-Translational Modification：O00264 has two isomers: O00264-1: 21671 Da (predicted); O00264-2: 15879 Da (predicted).
O-glycosylated; contains chondroitin sulfate attached to Ser-54
Subunit：Homodimer
Synonyms
HPR6.6 antibody; Membrane associated progesterone receptor component 1 antibody; Membrane-associated progesterone receptor component 1 antibody; mPR antibody; PGRC1_HUMAN antibody; PGRMC antibody; Pgrmc1 antibody; Progesterone binding protein antibody; Progesterone receptor membrane component 1 antibody
ドキュメンテーション
User Guide for Antibodies (1077 KB)

PGRMC1 Antibody (YA6966) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
PGRMC1 Antibody (YA6966)
製品番号:
HY-P87283
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