1. PROTAC
  2. PROTAC Linker
  3. 6-Maleimidocaproic acid sulfo-NHS

6-Maleimidocaproic acid sulfo-NHS 

Cat. No.: HY-136158
Handling Instructions

6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

6-Maleimidocaproic acid sulfo-NHS Chemical Structure

6-Maleimidocaproic acid sulfo-NHS Chemical Structure

CAS No. : 103848-61-9

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Description

6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

Molecular Weight

388.35

Formula

C₁₄H₁₆N₂O₉S

CAS No.

103848-61-9

SMILES

O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCCCN2C(C=CC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

Keywords:

6-Maleimidocaproic acid sulfo-NHSPROTAC LinkerInhibitorinhibitorinhibit

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Product name:
6-Maleimidocaproic acid sulfo-NHS
Cat. No.:
HY-136158
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