CLK1/4-IN-1
CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer.
For research use only. We do not sell to patients.
- CAS No.: 3029431-90-8
- Formula: C18H14ClNO4S
- Molecular Weight:375.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CLK1 9.7 nM (IC50) |
CLK4 6.6 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-24 | GI50 |
1.1 μM
Compound: 31
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Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 3 days by MTT assay
Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 3 days by MTT assay
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[PMID: 35635953] |
Chemical Information
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CAS No. 3029431-90-8
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Molecular Weight 375.83
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Formula C18H14ClNO4S
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SMILES
O=C(NC(C1=C(C=CC(Cl)=C1)OC)=O)C2=CC3=CC(OC)=CC=C3S2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CLK1/4-IN-1 Related Classifications
HY-146335 Related Classifications
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