1. Cell Cycle/DNA Damage
  2. CDK
  3. CLK1/4-IN-1

CLK1/4-IN-1 

Cat. No.: HY-146335
Handling Instructions

CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer.

For research use only. We do not sell to patients.

CLK1/4-IN-1 Chemical Structure

CLK1/4-IN-1 Chemical Structure

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Description

CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer[1].

IC50 & Target[1]

CLK1

9.7 nM (IC50)

CLK4

6.6 nM (IC50)

Molecular Weight

375.83

Formula

C18H14ClNO4S

SMILES

O=C(N1[H]O(C2=C(C1=O)C=C(Cl)C=C2)C)C3=CC4=CC(OC)=CC=C4S3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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CLK1/4-IN-1
Cat. No.:
HY-146335
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