3029431-90-8
3029431-90-8
Chemical Structure
CLK1/4-IN-1
- CAS No.: 3029431-90-8
- Formula:C18H14ClNO4S
- Molecular Weight:375.83
IUPAC Name: N-(5-chloro-2-methoxybenzoyl)-5-methoxybenzo[b]thiophene-2-carboxamide
InChIKey: YQLKBWUOUBOKRE-UHFFFAOYSA-N
SMILES: O=C(NC(C1=C(C=CC(Cl)=C1)OC)=O)C2=CC3=CC(OC)=CC=C3S2
Biological Activity: CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer[1].
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CLK1/4-IN-1 | CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer. | |||||||||||||||||||||
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References
Keywords
