Cathepsin L-IN-6
Cathepsin L-IN-6 (Compound 6a) is a selective cathepsin L inhibitor with an IC50 of 0.021 μM. Cathepsin L-IN-6 suppresses cathepsin L activity by directly binding to cathepsin L. Cathepsin L-IN-6 inhibits IL-6 and IL-8. Cathepsin L-IN-6 shows a high anti-inflammatory activity. Cathepsin L-IN-6 can be used in the research of acute lung injury.
For research use only. We do not sell to patients.
- CAS No.: 3077842-39-5
- Formula: C24H23FN4O2
- Molecular Weight:418.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Cathepsin Isoforms
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Biological Activity
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cathepsin L 0.021 μM (IC50) |
Cathepsin B 7.41 μM (IC50) |
Cathepsin C 27.92 μM (IC50) |
cathepsin S 5.87 μM (IC50) |
CTSH 0.627 μM (IC50) |
IL-6 |
IL-8 |
Chemical Information
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CAS No. 3077842-39-5
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Molecular Weight 418.46
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Formula C24H23FN4O2
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SMILES
O=C(C1=CC=C(C=C1)F)NCCCCCN2C=CC3=C(N=CN=C32)OC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)