5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone
5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone (compound 1), a flavonoid, is a potent ABCG2 inhibitor with an IC50 of 6.6 μM.
For research use only. We do not sell to patients.
- CAS No.: 1268140-15-3
- Formula: C21H22O6
- Molecular Weight:370.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H460 | IC50 |
6.6 μM
Compound: 1
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Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin C
Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin C
|
[PMID: 21275386] |
Chemical Information
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CAS No. 1268140-15-3
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Molecular Weight 370.40
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Formula C21H22O6
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SMILES
O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2O[C@H](C3=CC(O)=C(C=C3)OC)C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)