1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Carebastine

Carebastine 

Cat. No.: HY-121356
Handling Instructions

Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner. Carebastine suppresses the expression of macrophage migration inhibitory factor.

For research use only. We do not sell to patients.

Carebastine Chemical Structure

Carebastine Chemical Structure

CAS No. : 90729-42-3

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1 mg USD 55 In-stock
Estimated Time of Arrival: December 31
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Description

Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].

IC50 & Target[1][2]

H1 receptor

 

Molecular Weight

499.64

Formula

C₃₂H₃₇NO₄

CAS No.

90729-42-3

SMILES

O=C(CCCN1CCC(OC(C2=CC=CC=C2)C3=CC=CC=C3)CC1)C4=CC=C(C=C4)C(C)(C(O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
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Carebastine
Cat. No.:
HY-121356
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