Z169667518
Z169667518 is a ligand of IL-6. Z169667518 can inhibit IL-6-induced STAT3 reporter activity with an IC50 of 2.7 µM. Z169667518 can be used in the research of IL-6-related diseases.
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- CAS. Nr.: 941127-19-1
- Formel: C23H18N4O
- Molecular Weight:366.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
IL-6 |
STAT3 |
Chemical Information
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CAS. Nr. 941127-19-1
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Molecular Weight 366.42
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Formel C23H18N4O
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SMILES
O=C(C1=CC=C(C=C1)C#CC2=CC=CC=C2)NCCC3=NN=C4C=CC=CN43
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)