JAK3-IN-17
JAK3-IN-17 (Compound X15) is an orally active JAK3 inhibitor (IC50: 14.56 nM). JAK3-IN-17 inhibits the production of IL-2 and IL-6 in a DNCB-induced mouse atopic dermatitis model and exhibits anti-inflammatory activity.
For research use only. We do not sell to patients.
- Formula: C21H15FN4O
- Molecular Weight:358.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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JAK3 14.56 nM (IC50) |
Chemical Information
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Molecular Weight 358.37
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Formula C21H15FN4O
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SMILES
O=C(C=C)NC1=CC=CC(C2=CN=C3C=CC(C4=C(F)N=CC=C4)=CN32)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)