NHE3-IN-3
NHE3-IN-3 (Compound 1) is a Na+/H+ exchanger isoform 3 (NHE3) inhibitor with pIC50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague–Dawley rats.
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- CAS No.: 543734-50-5
- 화학식: C16H16Cl2N2O2S
- 분자량:371.28
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
pIC50: 6.6 (rat NHE3), 6.2 (human NHE3)[1]
Chemical Information
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CAS No. 543734-50-5
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분자량 371.28
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화학식 C16H16Cl2N2O2S
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SMILES
CN1CC2=C(C(C1)C3=CC(S(N)(=O)=O)=CC=C3)C=C(C=C2Cl)Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NHE3-IN-3 Related Classifications
HY-151360 Related Classifications
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