NHE3-IN-3
NHE3-IN-3 (Compound 1) is a Na+/H+ exchanger isoform 3 (NHE3) inhibitor with pIC50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague–Dawley rats.
For research use only. We do not sell to patients.
- CAS No.: 543734-50-5
- Formula: C16H16Cl2N2O2S
- Molecular Weight:371.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
pIC50: 6.6 (rat NHE3), 6.2 (human NHE3)[1]
Chemical Information
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CAS No. 543734-50-5
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Molecular Weight 371.28
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Formula C16H16Cl2N2O2S
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SMILES
CN1CC2=C(C(C1)C3=CC(S(N)(=O)=O)=CC=C3)C=C(C=C2Cl)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)