Apoptosis inducer 42
Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer.
For research use only. We do not sell to patients.
- CAS No.: 66685-93-6
- Formula: C11H13OPS
- Molecular Weight:224.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-6 |
Apoptosis inducer 42 (Compound 11) inhibits SW480, SW620, PC3f, HCT116 and HaCaT cells growth with IC50 values of 5.1, 6.3,6.0, 4.4 and 14.2 μM, respectively[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) reduces the amount of live cells in SW480, SW620, PC3f and HCT116 cells[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) activates late apoptosis and inhibits IL-6 secretion in SW480, SW620, PC3f and HCT116 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SW480, SW620, PC3f and HCT116 cells
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Concentration:5.1 μM in SW480, 6.3 μM in SW620, 6.0 μM in PC3f, 4.4 μM in HCT116 cells
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Incubation Time:72 h
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Result:Activated >80% late apoptosis.
Chemical Information
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CAS No. 66685-93-6
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Molecular Weight 224.26
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Formula C11H13OPS
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SMILES
O=C1CCP(C2=CC=CC=C2)(CC1)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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