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SI-W052

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SI-W052 is an orally active, brain-penetrant and selective small-molecule inhibitor targeting mTOR and TEX264. SI-W052 activates autophagy by inhibiting mTOR phosphorylation and enhances TEX264 expression to promote ER turnover, suppressing LPS-induced release of inflammatory factors (TNF-α, IL-6). SI-W052 is promising for research of Alzheimer’s disease (AD)-associated neuroinflammation.

For research use only. We do not sell to patients.

  • Purity: 98.0%
  • CAS No.: 2572552-60-2
  • Formula: C20H19ClN2O5S
  • Molecular Weight:434.89
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • SI-W052 Chemical Structure
    SI-W052 Chemical Structure
CAS No.: 2572552-60-2
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All mTOR Isoforms

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All Interleukin Related Isoforms

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100 mg

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  • SI-W052 Chemical Structure
    SI-W052 Chemical Structure
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  • SI-W052