Anti-inflammatory agent 76
Anti-inflammatory agent 76 (Compd 8b), an anti-inflammatory agent, exhibits good NO, IL-1β and IL-6 inhibitory activities.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C26H17FO5
- 분자량:428.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
0.66 μg/mL
Compound: 8b
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Antiinflammatory activity in LPS activated mouse RAW264.7 cells assessed as inhibition of NO production
Antiinflammatory activity in LPS activated mouse RAW264.7 cells assessed as inhibition of NO production
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[PMID: 38522589] |
| RAW264.7 | IC50 |
1.54 μM
Compound: 8b
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Antiinflammatory activity in LPS activated mouse RAW264.7 cells assessed as inhibition of NO production
Antiinflammatory activity in LPS activated mouse RAW264.7 cells assessed as inhibition of NO production
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[PMID: 38522589] |
In Vitro
Anti-inflammatory agent 76 (Compd 8b) shows high potent NO inhibitory activity in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells with an IC50 of 1.54 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 428.41
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화학식 C26H17FO5
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SMILES
COC(C=C1)=C(F)C=C1[C@H]2[C@H](C(C3=CC=CC=C3)=O)OC4=C2C(C5=CC=CC=C5C4=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-inflammatory agent 76 Related Classifications
HY-161396 Related Classifications
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