6-Bromohexanoic acid
Based on 1 Customer Validation
6-Bromohexanoic acid (6-bromohexanoate) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.59%
- CAS No.: 4224-70-8
- Formula: C6H11BrO2
- Molecular Weight:195.06
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E435 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4224-70-8
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Appearance Solid
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Molecular Weight 195.06
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Formula C6H11BrO2
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Color White to off-white
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SMILES
O=C(O)CCCCCBr
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Synonyms
6-bromohexanoate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (512.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1266 mL | 25.6331 mL | 51.2663 mL | 128.1657 mL |
| 5 mM | 1.0253 mL | 5.1266 mL | 10.2533 mL | 25.6331 mL | |
| 10 mM | 0.5127 mL | 2.5633 mL | 5.1266 mL | 12.8166 mL | |
| 15 mM | 0.3418 mL | 1.7089 mL | 3.4178 mL | 8.5444 mL | |
| 20 mM | 0.2563 mL | 1.2817 mL | 2.5633 mL | 6.4083 mL | |
| 25 mM | 0.2051 mL | 1.0253 mL | 2.0507 mL | 5.1266 mL | |
| 30 mM | 0.1709 mL | 0.8544 mL | 1.7089 mL | 4.2722 mL | |
| 40 mM | 0.1282 mL | 0.6408 mL | 1.2817 mL | 3.2041 mL | |
| 50 mM | 0.1025 mL | 0.5127 mL | 1.0253 mL | 2.5633 mL | |
| 60 mM | 0.0854 mL | 0.4272 mL | 0.8544 mL | 2.1361 mL | |
| 80 mM | 0.0641 mL | 0.3204 mL | 0.6408 mL | 1.6021 mL | |
| 100 mM | 0.0513 mL | 0.2563 mL | 0.5127 mL | 1.2817 mL |
6-Bromohexanoic acid Related Classifications
HY-W007559 Related Classifications
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