1. Immunology/Inflammation Apoptosis
  2. Toll-like Receptor (TLR) Interleukin Related TNF Receptor
  3. M199

M199 is a potent TLR3/9 signaling inhibitor. M199 induces secretion of IL-6, IL-8 and TNFα in human PBMCs. M199 is used as a selective inducer of the immune response.

For research use only. We do not sell to patients.

M199 Chemical Structure

M199 Chemical Structure

CAS No. : 1051933-86-8

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Description

M199 is a potent TLR3/9 signaling inhibitor. M199 induces secretion of IL-6, IL-8 and TNFα in human PBMCs. M199 is used as a selective inducer of the immune response[1].

IC50 & Target[1]

TLR3

 

TLR9

 

IL-6

 

IL-8

 

Molecular Weight

279.34

Formula

C17H17N3O

CAS No.
SMILES

O=C(NCC)NC1=CC2=C(N=C3C=CC=CC3=C2C=C1)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
M199
Cat. No.:
HY-114592
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