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Cat. No.: HY-123285

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UK 14819

(Synonyms: 5-Desbromo, 5-chloro brimonidine)

UK 14819 (5-Desbromo, 5-chloro brimonidine) is an α2-adrenoceptor agonist. UK 14819 inhibits stimulation-induced contractions of rabbit distal colon with an IC₅₀ of 6.66 nM.

For research use only. We do not sell to patients.

CAS No.: 91147-46-5
Formula: C₁₁H₁₀ClN₅
Molecular Weight:247.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

UK 14819 Chemical Structure

CAS No.: 91147-46-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

UK 14819 (5-Desbromo, 5-chloro brimonidine) is an α2-adrenoceptor agonist. UK 14819 inhibits stimulation-induced contractions of rabbit distal colon with an IC₅₀ of 6.66 nM^[1].

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 91147-46-5
Molecular Weight 247.69
Formula C₁₁H₁₀ClN₅
SMILES

ClC1=C2N=CC=NC2=CC=C1NC3=NCCN3
Synonyms

5-Desbromo, 5-chloro brimonidine
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thaina P, et al. Inhibition by alpha 2-adrenoceptor agonists of contractions of rabbit isolated colon elicited by pelvic nerve stimulation. J Auton Pharmacol. 1993 Apr;13(2):115-26. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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UK 14819

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

UK 14819 Related Classifications

HY-123285 Related Classifications