Anti-CD54/ICAM-1 Antibody (R6-5-D6)
Anti-CD54/ICAM-1 Antibody (R6-5-D6) is a kind of mouse IgG2a chimeric antibody inhibitor, targeting to human CD54/ICAM-1. Anti-CD54/ICAM-1 Antibody (R6-5-D6) can block CD54 binding to its ligand Lymphocyte Function-Associated Antigen 1 (LFA-1). Anti-CD54/ICAM-1 Antibody (R6-5-D6) can be used for the researches of inflammation and immunology.
For research use only. We do not sell to patients.
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Isotype
Mouse IgG2a kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD54/ICAM-1
In Vitro
Anti-CD54/ICAM-1 Antibody (R6-5-D6) (10 μg/mL, 10 days) induces cells differentiate to Treg phenotype in human naïve CD4+ T cells[1].
Anti-CD54/ICAM-1 Antibody (R6-5-D6) (2-12 μg/mL, 15 mins) reduces baseline adherence and the enhancement caused by IL-l or LPS (HY-D1056) stimulation in human umbilical vein endothelial cells (HUVEC) [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Application
in vitro blocking of CD54; in vivo imaging; Functional Assays; Flow Cytometry; Immunofluorescenc
Chemical Information
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Molecular Weight 150 kDa
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SMILES
[Anti-CD54/ICAM-1 Antibody (R6-5-D6)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Williams KM, et al. Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation. Cell Immunol. 2011;271(2):418-27. [Content Brief]
[2]. Smith CW, et al. Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migration. J Clin Invest. 1988 Nov;82(5):1746-56. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-CD54/ICAM-1 Antibody (R6-5-D6) Related Classifications
HY-P990857 Related Classifications
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