PROTAC HPK1 Degrader-6
PROTAC HPK1 Degrader-6 (314) is a highly efficient and effective PROTAC degrader targeting HPK1 (IC50 < 50 nM). PROTAC HPK1 Degrader-6 can be used for the study of leukemia. Red: HPK1 ligand (HY-179196); Blue: E3 ligase CRBN ligand (HY-179197).
(Pink: HPK1 ligand (HY-179196); Blue: Cereblon ligand (HY-179197); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3099168-12-1
- Formula: C41H43N9O3
- Molecular Weight:709.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3099168-12-1
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Molecular Weight 709.84
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Formula C41H43N9O3
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SMILES
O=C(N1)N(C2=CC=C(C3CCN(C4CN(C5=CC=C(NC6=NC=C7C=CC(C8=CN=C9OCCNC9=C8C)=CC7=N6)C=C5)C4)CC3)C=C2C)CCC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)