[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2
[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 (Compound 3) is a copper complex, which inhibits cell viability of HCT116, HCT116DoxR, A2780 and fibroblasts, with IC50s of 0.13, 0.15, 0.66 and 6.24 μM, respectively. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 induces apoptosis and autophagy, and arrests cell cycle at G0/G1 phase in HCT116DoxR. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 exhibits antimetastatic efficacy.
For research use only. We do not sell to patients.
- Formula: C52H38Cl2Cu2F12N6O2P22-
- Molecular Weight:1266.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 1266.82
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Formula C52H38Cl2Cu2F12N6O2P22-
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SMILES
COC1=C2C(C=CC=C2)=C(C=C1)C3=CC(C4=[N]5C=CC=C4)=[N]6C(C7=CC=CC=[N]7[Cu]658Cl[Cu]9%10([N]%11=CC=CC=C%11C%12=CC(C%13=C%14C=CC=CC%14=C(C=C%13)OC)=CC(C%15=CC=CC=[N]%15%10)=[N]%129)Cl8)=C3.[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].[2+]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)