Taxamairin B
Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice.
For research use only. We do not sell to patients.
- CAS No.: 110300-77-1
- Formula: C22H24O4
- Molecular Weight:352.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 110300-77-1
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Molecular Weight 352.42
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Formula C22H24O4
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SMILES
CC(C1=C2)(C)C(C=CC1=CC3=C(C=C(C(C)C)C(OC)=C3OC)C2=O)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Liu M, et al. Rapid access to icetexane diterpenes: Their protective effects against lipopolysaccharides-induced acute lung injury via PI3K/AKT/NF-κB axis in macrophages. Eur J Med Chem. 2023 Nov 15;260:115769. [Content Brief]
[2]. Liang JY, et al. Two new antineoplastic diterpenes from Taxus mairei. Chem Pharm Bull (Tokyo). 1987 Jun;35(6):2613-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)